Results 211 to 220 of about 173,276 (306)

Association of Different Types of Diabetic Autonomic Neuropathy With Left Ventricular Diastolic Dysfunction in Patients With Type 2 Diabetes: A Cross-Sectional Study. [PDF]

J Diabetes
Feng R, Yan D, Bai M, Ran X, Chen D, Wang C, Chen L, Lin S, He S, Liu Y, Wu M, Lei Z, Gao Y.   +12 more
europepmc   +1 more source

The first case of Reel Syndrome in a dog after pacemaker implantation: A case report

Australian Veterinary Journal, EarlyView.
Reel Syndrome is a rare complication of permanent pacemaker implantation, characterised by the rotation of the device around its transverse axis, which causes the lead to coil around the generator and displacement, leading to pacing dysfunction. This report presents the first documented case of Reel Syndrome in a dog.
Z Wojtczak, M Lewicki, M Płóciennik, J Gach, K Nowak, A Noszczyk‐Nowak   +5 more
wiley   +1 more source

Trimethylamine N-Oxide as a Biomarker for Left Ventricular Diastolic Dysfunction and Functional Remodeling After STEMI. [PDF]

Int J Mol Sci
Tsai TY, Aldujeli A, Haq A, Murphy P, Unikas R, Sharif F, Garg S, Brilakis ES, Onuma Y, Serruys PW.   +9 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

T2D-LVDD: neural network-based predictive models for left ventricular diastolic dysfunction in type 2 diabetes. [PDF]

Diabetol Metab Syndr
Rong Y, Liu W, Li K, Guo J, Li XP.
europepmc   +1 more source

Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity

British Journal of Pharmacology, EarlyView.
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand, Simone Brogi, Mustafa Tezeren, Andrea Tafi, Omer H. Ocak, Hasan Koyuncu, Igor Tetko, Laurent Désaubry, Canan G. Nebigil   +8 more
wiley   +1 more source

Left Ventricular Diastolic Dysfunction and Its Predictive Factors Among Saudi Patients With Type 2 Diabetes Mellitus. [PDF]

J Clin Med Res
Aldhahi RA, Barhoush MM, Almunif DS, Anabi MJM, Aburisheh KH.   +4 more
europepmc   +1 more source

Pharmacological treatment with a GABA(A) receptor modulator and a selective serotonin reuptake inhibitor as a mitigation strategy against aircraft noise‐induced cardiovascular and neuronal damage

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Noise pollution, particularly by aircraft, is a significant risk factor for cardiovascular disease. Aircraft noise activates stress response pathways in the brain, via the amygdala, the sympathetic nervous system and the hypothalamic–pituitary–adrenal axis.
Ivana Kuntić, Marin Kuntić, Jiayin Zheng, Leonardo Nardi, Matthias Oelze, Arijan Valar, Dominika Mihaliková, Lea Strohm, Hans‐Georg Buchholz, Nicole Bausbacher, Simon Lange, Henning Ubbens, Qi Tang, Liyu Zhang, Guilherme Horta, Paul Stamm, Omar Hahad, Axel Methner, Sebastian Steven, Huige Li, Mathias Schreckenberger, Dilja Krueger‐Burg, Adrian Gericke, Michael J. Schmeisser, Thomas Münzel, Andreas Daiber   +25 more
wiley   +1 more source

Prevalence and prognostic significance of pulmonary hypertension in adults with left ventricular diastolic dysfunction. [PDF]

Open Heart
Ratwatte S, Playford D, Strange G, Celermajer DS, Stewart S.   +4 more
europepmc   +1 more source

Neurokinin‐1 receptor activation protects against cardiac fibrosis, inflammation and diastolic dysfunction in type 2 diabetic mice

British Journal of Pharmacology, EarlyView.
Background and Purpose The pathogenesis of type 2 diabetes mellitus (T2DM)‐induced cardiomyopathy involves cardiac fibrosis that leads to diastolic dysfunction. We established that replacement of lost substance P (SP) that occurs in T2DM reduces cardiac fibrosis and decreases inflammation in T2DM mice and non‐human primates.
Alexander Widiapradja, Heather Connery, Brody J. Helmick, Kallie J. Schafner, Vamsi Manchikalapudi, Hannah Horvath, Sophia Gugino, Tamas Kriska, Anja Herrnreiter, Evan DeVallance, William B. Campbell, Scott P. Levick   +11 more
wiley   +1 more source