Results 51 to 60 of about 176,565 (312)

Diastolic And Systolic Right Ventricular Dysfunction Precedes Left Ventricular Dysfunction In Patients Paced From Right Ventricular Apex [PDF]

, 2006
Background: Cardiac dysfunction after right ventricular (RV) apical pacing is well known but its extent, time frame of appearance and individual effect on left ventricular (LV), RV systolic and diastolic parameters has not evaluated in a systematic ...
Bansal, Sandeep, M, Hasan, MK, Makharia, Puri, Aniket, RK, Saran, SK, Dwivedi, VK, Puri, VS, Narain   +7 more
core  

Progression of Coronary Artery Calcium and Incident Heart Failure: The Multi-Ethnic Study of Atherosclerosis. [PDF]

, 2017
BackgroundAlthough the association between coronary artery calcium (CAC) and future heart failure (HF) has been shown previously, the value of CAC progression in the prediction of HF has not been investigated.
Ambale-Venkatesh, Bharath, Bahrami, Hossein, Bakhshi, Hooman, Bluemke, David A, Budoff, Matthew, Lima, João AC, Ostovaneh, Mohammad R, Wong, Nathan D, Wu, Colin O, Yang, Xiaoying   +9 more
core   +2 more sources

A Systemic Selective Modified mRNA Delivery Platform for Preventing Chemotherapy‐Induced Cardiotoxicity

Advanced Science, EarlyView.
In Yoo and Mainkar et al., we present a minimally invasive, CM‐selective modRNA delivery system encapsulated in lipid nanoparticles for intravenous (IV) administration. This platform enables selective cardiac translation of therapeutic modRNA but suppresses expression in off‐target tissues, including tumors.
Jimeen Yoo, Gayatri Mainkar, Matteo Ghiringhelli, Bernardo Gindri Dos Santos, Magdalena M. Żak, Keerat Kaur, Ann Anu Kurian, Matthew Adjmi, Segev Sharon, Eftychia Markopoulou, Lucia Žigová, Daniela Hirsch, Sydney Pessin, Rachel Hanan, Juan Luis Escano Abreu, Niki Brisnovali, Nicole Dubois, Leigh Goedeke, Mengcheng Shen, Lior Zangi   +19 more
wiley   +1 more source

Right Heart Remodeling in Patients with End-Stage Alcoholic Liver Cirrhosis: Speckle Tracking Point of View [PDF]

, 2019
BACKGROUND: Data regarding cardiac remodeling in patients with alcoholic liver cirrhosis are scarce. We sought to investigate right atrial (RA) and right ventricular (RV) structure, function, and mechanics in patients with alcoholic liver cirrhosis.
Braun, Alexander, Cuspidi, Cesare, Heinzel, Frank, Koeckritz, Francisca von, Pieske, Burkert, Schmuck, Rosa B., Tadic, Marijana, Teegen, Eva M., Zhang, Kun   +8 more
core   +1 more source

Reprogramming the Myocardial Infarction Conductive Microenvironment with Superconductive Ionic Patch for Cardiac Function Repair

Advanced Science, EarlyView.
A super‐conductive ionic patch reprograms the post‐infarction microenvironment by enabling stable ionic migration and electrical signal transmission within damaged myocardium. The patch rapidly adheres to cardiac tissue, enhances conduction velocity, suppresses excitation‐contraction decoupling, and promotes structural and functional cardiac repair in ...
Changyong Wang, Zhuang Zhang, Qi Yin, Changgeng Xu, Linlin Liang, Siwei Li, Yuwei Zhao, Chunlan Wang, Jin Zhou   +8 more
wiley   +1 more source

Evaluation of diastolic dysfunction in children with hypertrophic cardiomyopathy and its relationship with development of myocardial fibrosis

The Egyptian Heart Journal, 2023
Background Patients with hypertrophic cardiomyopathy may develop symptoms of shortness of breathing due to diastolic dysfunction which is not related to the severity of left ventricular outflow tract obstruction.
Salem Elsayed Deraz, Omar Deyaa Esmat, Rehab Galal Abd El-Hmid, Sayed Ali Amin   +3 more
doaj   +1 more source

Multimodality Imaging Clues for Restrictive Cardiomyopathy

Journal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2022
Restrictive cardiomyopathy is an entity that can be mistaken for several mimicking conditions, including hypertrophic cardiomyopathy. These patients present with heart failure, which is essentially due to left ventricular diastolic dysfunction, with ...
Srilakshmi M Adhyapak, Grace A Thomas, Anuraag Gupta, Jabraan U Shaikh, Tivlin Jose, Harshith Kramadhari, Kiron Varghese   +6 more
doaj   +1 more source

Hypoxia induces dilated cardiomyopathy in the chick embryo: mechanism, intervention, and long-term consequences [PDF]

, 2009
Background: Intrauterine growth restriction is associated with an increased future risk for developing cardiovascular diseases. Hypoxia in utero is a common clinical cause of fetal growth restriction.
AM Katz, AN Tintu, Andrei Tintu, Anne Cathrine Staff, Arnold Schwartz, Asif Ahmed, BO Verburg, C Holubarsch, CP Leeson, DE Stewart, DJ Barker, E Villamor, EA Dumont, Edgar Hernandez-Andrade, Eduard Gratacos, Ellen Rouwet, Erdal Safak, EV Rouwet, Fatima Crispi, Ferdinand le Noble, FJ Giordano, G Pardi, H Haase, H Sugimoto, HQ Miao, I Shiojima, Ingo Morano, Irene Cetin, J Schaper, JL Morrison, Joep Brinkmann, JR Ingelfinger, KH Nicolaides, L Miquerol, L van Heerebeek, Leo Hofstra, M Feucht, M Ream, Marc Tjwa, Marc van Bilsen, Michael Jacobs, MR Zile, MR Zile, MW Gillman, N Ferrara, P Carmeliet, Peter Carmeliet, R Tatsumi, S Gupta, S Hein, S Hein, S Louey, SF Nagueh, Shakil Ahmad, SK Sharma, Stefan Verlohren, TA Fong, TM Nosek, Wouter H. Lamers, X Yue, Y Dor, Y Sugishita, Y Wu   +62 more
core   +8 more sources

Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism

Advanced Science, EarlyView.
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying, Hangping Fan, Yunhe Wang, Ruhong Jiang, Dongsheng Cai, Hui Cheng, Hao Wang, Chenyang Jiang, Ping Liang   +8 more
wiley   +1 more source

TLR4 and NLRP3 Caspase 1- IL-1β- Axis are not Involved in Colon Ascendens Stent Peritonitis (Casp)-Associated Heart Disease [PDF]

, 2018
Hemodynamic collapse and myocardial dysfunction are among the major causes ofdeath in severe sepsis. The purpose of this study was to assess the role played by TLR4and by the NLRP3 inflammasome in the cardiac dysfunction that occurs after ...
Branda, Hugo Justino, Carvalho, Adriana Bastos, Fernandez Ruocco, Maria Julieta, Ferreira, Fabiano, López Alarcón, Maria Micaela, Medei, Emiliano, Neto Paiva, Claudia, Paula Neto, Heitor A., Peroba Ramos, Isalira, Sepúlveda, Marisa Noemí, Vila Petroff, Martin Gerarde   +10 more
core   +2 more sources