Results 191 to 200 of about 147,367 (260)

Chronic high‐altitude exposure and intracerebral hemorrhage: A novel perspective from the vascular‐immune‐neuronal network

Neuroprotection, EarlyView.
Long‐term chronic high‐altitude hypobaric hypoxia increases susceptibility to ICH, particularly among migrant populations lacking EPAS1/SENP1 adaptive genetic variants relative to high‐altitude indigenous residents. Persistent hypoxia initiates blood–brain barrier (BBB) breakdown, aberrant glial and immune activation, and progressive neuronal injury ...
Rongsu Huang, Linjie Wei, Mingxi Li, Bo Wu, Rongjian Ouyang, Gang Zhu, Yujie Chen   +6 more
wiley   +1 more source

Impact of baseline left ventricular ejection fraction and body mass index on the effect of 24-week Ipragliflozin treatment on left ventricular diastolic function in patients with type 2 diabetes and chronic kidney disease: insights from the PROCEED trial. [PDF]

Cardiovasc Diabetol
Teragawa H, Tanaka A, Takahashi K, Oshita C, Uchimura Y, Kamei N, Hirai H, Shimabukuro M, Taguchi I, Okada Y, Node K.   +10 more
europepmc   +1 more source

Obesity Increases Cardiovascular Strain During Passive Whole‐Body Heat Stress in Middle‐Aged Women

Obesity, EarlyView.
ABSTRACT Objective Heat‐related mortality is greater in middle‐aged and older women, compared with age‐matched men, and in those with obesity, although the causes are unclear. Methods Thermoregulatory and cardiovascular responses were assessed in (n = 10 per group) young women (21 ± 2 years), middle‐aged women without obesity (−OB; 55 ± 6 years), and ...
Georgia R. Davila, Sandra N. Fredericks, William E. Jennings, Emily A. Haskell, Jamie A. Cooper, S. Tony Wolf   +5 more
wiley   +1 more source

Cardiovascular and Hemodynamic Adaptations in Selective Fetal Growth Restriction: A Cohort Study of Monochorionic Twins

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective In monochorionic diamniotic twins with selective fetal growth restriction (sFGR), the Gratacós type is defined by one vessel in one fetus. We asked how much cerebral, venous and myocardial divergence between co‐twins it captures. Method Single‐center combined retrospective–prospective cohort; one diagnostic examination per pregnancy.
Tanchanok Auwattanamongkol, Nisarat Phithakwatchara, Katika Nawapun, Sommai Viboonchart, Suparat Jaingam, Kanokwaroon Watananirun, Sriwipa Kaewsrinual, Tuangsit Wataganara   +7 more
wiley   +1 more source

The moderating effect of fluid overload on the relationship between the augmentation index and left ventricular diastolic function in patients with CKD. [PDF]

Sci Rep
Han BG, Pak D, Kim JS, Sohn Y.
europepmc   +1 more source

Transplacental Flecainide and/or Digoxin for Fetal Tachyarrhythmias: Therapeutic Efficacy and Clinical Experience

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To assess the efficacy and safety of transplacental flecainide and/or digoxin for fetal tachyarrhythmias when sotalol is unavailable. Method We evaluated transplacental flecainide, digoxin, or combination therapy in a retrospective and prospective cohort across two Thai tertiary centers.
Mukpradab Darakamas, Sanitra Anuwutnavin, Fuanglada Tongprasert, Wisit Chankhunaphas, Kanyarat Nilto, Supaluck Kanjanauthai, Jarupim Soongswang   +6 more
wiley   +1 more source

Is early use of sodium-glucose cotransporter type 2 inhibitor (SGLT2i) necessary even in diabetic patients without cardiovascular disease: a prospective study regarding the effect of SGLT2i on left ventricular diastolic function. [PDF]

J Cardiovasc Imaging
Jeon K, Jang SY, Lee YB, Kim J, Kim D, Chang SA, Park SJ, Lee SC, Park SW, Lee MK, Kim EK, Hur KY.   +11 more
europepmc   +1 more source

High‐intensity interval training vs. moderate‐intensity continuous training in COVID‐19 survivors (COVIDEX): A randomized clinical trial on feasibility and short‐term efficacy

PM&R, EarlyView.
Abstract Background High‐intensity interval training (HIIT) and moderate‐intensity continuous training (MICT) have been widely studied in individuals with chronic conditions. However, no studies have compared these two exercise modalities in COVID‐19 survivors. Objective To compare the feasibility, safety, adherence, and short‐term efficacy of HIIT and
Vinicius Afonso Gomes, William de Suzart, Fabiane Costa Santos Fontoura, Micheli Bernardone Saquetto, Ana Paula Bastos Nery, Bruno Prata Martinez, Thaiana Marcelino Ramos, Samara Souza Santos, Paulo Matheus Petersen Rivas, Ana Paula Andrade Barreto, Marcelo Chalhoub Coelho Lima, Mansueto Gomes‐Neto   +11 more
wiley   +1 more source

Multitarget Regulatory Mechanisms and Research Advances of Plant‐Derived Bioactive Ingredients in Hypertension Prevention and Management

Phytotherapy Research, EarlyView.
Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng, Yonglin Zhang, Jing Pan, Jing Luo, Hualin Sun, Chaonian Li, Li Li   +6 more
wiley   +1 more source

Integrative Approaches in Cardiovascular Disease: The Role of Nutraceuticals in Heart Failure, Atrial Fibrillation, and Related Conditions

Phytotherapy Research, EarlyView.
Schematic representation of the shared pathophysiological mechanisms underlying heart failure (HF) and atrial fibrillation (AF), including inflammation, oxidative stress, endothelial dysfunction, and fibrosis. The figure highlights the clinical and mechanistic convergence of conventional pharmacological therapies and selected nutraceuticals in ...
Laura Beatrice Mattioli, Ivan Corazza, Roberta Budriesi, Luca Camarda, Maria Carelli, Alberto Spadotto, Igor Diemberger   +6 more
wiley   +1 more source