Results 71 to 80 of about 223,587 (353)

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Prophylactic use of carvedilol to prevent ventricular dysfunction in patients with cancer treated with doxorubicin [PDF]

, 2018
Objective: Deterioration in ventricular function is often observed in patients treated with anthracyclines for cancer. There is a paucity of evidence on interventions that might provide cardio-protection.
Abrar, Mohammed Burhan, Abuosa, Ahmed Mohamed, Ahmed, Adel H., Andejani, Abdulwahab, Cleland, John G.F., Elshiekh, Ayman Hassan, Kholeif, Mona A., Kinsara, Abdulhalim Jamal, Qureshi, Kahekashan   +8 more
core   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

Advanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang, Xiangheng Cai, Mengqi Li, Xue Liu, Junhui Xue, Ye Liu, Ding Ai, Xinyang Hu   +7 more
wiley   +1 more source

Left Ventricular Diastolic Function in Normal Human Pregnancy [PDF]

Circulation, 1999
Background —Little information is available about changes in left ventricular diastolic function during pregnancy. We used mitral inflow and pulmonary venous flow profiles to evaluate left ventricular diastolic function in 37 healthy pregnant women 26 to 41 years old (mean, 32 years).
A, Mesa, C, Jessurun, A, Hernandez, K, Adam, D, Brown, W K, Vaughn, S, Wilansky   +6 more
openaire   +2 more sources

Pacinian Corpuscle‐Inspired Strain Conversion Enables Ultrasensitive, Linear, and Broad‐Range Piezoelectric Sensing for Cardiovascular Health Monitoring

Advanced Science, EarlyView.
A bioinspired piezoelectric sensor mimicking Pacinian corpuscles is developed to enable ultrasensitive and linear pressure sensing. A multilayer grooved architecture converts normal pressure into in‐plane strain, delivering high sensitivity, wide linear range, and efficient energy harvesting, enabling high‐fidelity wrist pulse monitoring and ...
Qi Yang, Zhongqian Song, Shengjie Liu, Yingming Ma, Weiyan Li, Huijun Kong, Cuiyu Liu, Yu Bao, Li Niu   +8 more
wiley   +1 more source

Impact of atrial fibrillation on the cardiovascular system through a lumped-parameter approach [PDF]

, 2014
Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and bioengineering ...
Camporeale, Carlo, Guala, Andrea, Ridolfi, Luca, Scarsoglio, Stefania   +3 more
core   +2 more sources

Marfan Syndrome Associated With Intellectual Disability and Behavioral Anomalies: Further Evidence for the Effect of Compound Heterozygous Variants in FBN1 on Phenotypic Severity

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Marfan syndrome (MFS) is a rare connective tissue disorder characterized by involvement of the cardiovascular, ocular, and musculoskeletal systems. Pathogenic variants in FBN1 cause most of the MFS cases; however, intellectual disability (ID) is rarely observed. A non‐consanguineous Pakistani family with four affected individuals was recruited.
Azmatullah Khan, Naseebullah Kakar, Ainullah Kakar, Malte Spielmann, Sajid Malik   +4 more
wiley   +1 more source

Left ventricular diastolic function in congenital myotonic dystrophy [PDF]

Archives of Disease in Childhood, 1999
Examination of left ventricular function and conduction abnormalities in myotonic dystrophy.Twelve patients (median age, 13.7 years) with myotonic dystrophy had detailed electrocardiography and echocardiography performed. Echocardiographic parameters were compared with body surface area (BSA) matched median normal values.Fractional shortening was ...
F A, Bu'Lock, M, Sood, J V, De Giovanni, S H, Green   +3 more
openaire   +2 more sources

Characterization of di‐gital, tri‐gital, and tetra‐gital temporal movement of systolic blood pressure on the arterial pulse waveform of rats at different vascular stiffness

Animal Models and Experimental Medicine, EarlyView.
The example of the time dependent fluctuation of systolic pressure on rat arterial pulse waveform in ms. The four levels of the systolic pressure fluctuation show di‐gital, tri‐gital and tetra‐gital fluctuation. The red dots represent particular heartbeats. Abstract Background An arterial stiffness is an indicator of many cardiovascular diseases.
Anton Misak, Lenka Tomasova, Marian Grman, Karol Ondrias   +3 more
wiley   +1 more source

Midlife blood pressure predicts future diastolic dysfunction independently of blood pressure [PDF]

, 2016
OBJECTIVES: High blood pressure (BP) is associated with diastolic dysfunction, but the consequence of elevated BP over the adult life course on diastolic function is unknown.
Chaturvedi, N, Deanfield, J, Francis, D, Ghosh, AK, Hardy, R, Hughes, AD, Kuh, D, Mayet, J, MRC NSHD Scientific and Data Collection Team, Pellerin, D   +9 more
core   +1 more source