Results 61 to 70 of about 2,930,669 (250)
Digital Health, 2022 Background Artificial intelligence-enabled electrocardiogram has become a substitute tool for echocardiography in left ventricular ejection fraction estimation.
Chun-Ho Lee +8 more
doaj +1 more source
An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2
Advanced Science, EarlyView.Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu +7 more
wiley +1 more source
SAGE Open Medicine, 2016 Objectives: Left ventricular ejection fraction can be measured by a variety of invasive and non-invasive cardiac techniques. This study assesses the relation of three diagnostic modalities to each other in the measurement of left ventricular ejection ...
Nadish Garg +5 more
doaj +1 more source
Journal of the Saudi Heart Association, 2019 Objectives: To detect systolic dysfunction in heart failure with preserved ejection fraction (HFpEF) patients by using global longitudinal strain (GLS).
Hasanain Ali Hameed Bshiebish +2 more
doaj +1 more source
Physiological and clinical consequences of relief of right ventricular outflow tract obstruction late after repair of congenital heart defects. [PDF]
, 2006 BACKGROUND: Right ventricular outflow tract obstruction (RVOTO) is a common problem after repair of congenital heart disease. Percutaneous pulmonary valve implantation (PPVI) can treat this condition without consequent pulmonary regurgitation or ...
Sridharan, S +10 more
core
Effects of right ventricular pacing on left ventricular ejection fraction in a pacemaker clinic
, 2012 The aim of this study was to evaluate whether a change of left ventricular ejection fraction (LVEF) depending on percentage of right ventricular pacing is found in a real-life setting of a pacemaker ...
Schoenenberger, Andreas W +2 more
core +1 more source
Two Survival Tree Models for Myocardial Infarction Patients [PDF]
, 2000 In the search of a better prognostic survival model for post-acute myocardial infarction patients, the scientists at the Technical University of Munich's "Klinikum rechts der Isar" and the German Heart Center in Munich have developed some new parameters ...
Pashova, Victoria, Ulm, Kurt
core +1 more source
Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications
Advanced Science, EarlyView.Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen +11 more
wiley +1 more source
Advanced Science, EarlyView.Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang +17 more
wiley +1 more source
The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ
Advanced Science, EarlyView.UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi +6 more
wiley +1 more source