Results 71 to 80 of about 328,399 (303)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Accuracy of left ventricular ejection fraction by contemporary multiple gated acquisition scanning in patients with cancer: comparison with cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance, 2017
BackgroundMultiple gated acquisition scanning (MUGA) is a common imaging modality for baseline and serial assessment of left ventricular ejection fraction (LVEF) for cardiotoxicity risk assessment prior to, surveillance during, and surveillance after ...
Hans Huang, P. Nijjar, J. Misialek, A. Blaes, Nicholas P. Derrico, Felipe Kazmirczak, I. Klem, A. Farzaneh-Far, C. Shenoy   +8 more
semanticscholar   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

Advanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song, Hao Yang, Qiqi Zhang, Wenqin Zhou, Rui Wang, Yuxing Xie, Emeli Chatterjee, Guoping Li, Jizong Jiang, Qiulian Zhou, Cuimei Zhao   +10 more
wiley   +1 more source

Correlation Between Infarct Size and Hemodynamic Variables in ST-elevation Myocardial Infarction and Its Prognostic Implications

Indian Journal of Clinical Cardiology
Introduction A crucial prognostic marker for patients with ST-elevation myocardial infarction is infarct size. The present study was done to study the relationship between infarct size and invasive hemodynamics in patients with ST-elevation myocardial ...
Kumud Singh, Jayal Shah, Riyaz Charaniya, Krutika Patel, Akash Karwa, Govind Tiwari   +5 more
doaj   +1 more source

Case of Acute Graft Failure during Suspected Humoral Rejection with Preserved Ejection Fraction, but Severely Reduced Longitudinal Deformation Detected by 2D-Speckle Tracking

Case Reports in Transplantation, 2014
This case displays limited utility of left ventricular ejection fraction to detect acute graft failure due to microvascular vasculopathy and suspected humoral rejection.
Tor Skibsted Clemmensen, Hans Eiskjær, Pernille B. Kofoed-Nielsen, Søren Høyer, Steen Hvitfeldt Poulsen   +4 more
doaj   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Hypertensive heart disease: Benefit of carvedilol in hemodynamic, left ventricular remodeling, and survival

SAGE Open Medicine, 2019
Objectives: The aim of this study was to determine if carvedilol improved structural and functional changes in the left ventricle and reduced mortality in patients with hypertensive heart disease.
Renata F Dominguez, Valeria A da Costa-Hong, Luan Ferretti, Fabio Fernandes, Luiz A Bortolotto, Fernanda M Consolim-Colombo, Brent M Egan, Heno F Lopes   +7 more
doaj   +1 more source

Does quantitative left ventricular regional wall motion change after fibrous tissue resection in endomyocardial fibrosis?

Clinics, 2009
OBJECTIVES: We compared left ventricular regional wall motion, the global left ventricular ejection fraction, and the New York Heart Association functional class pre- and postoperatively.
Vera Maria Cury Salemi, Fabio Fernandes, Raquel Sirvente, Luciano Nastari, Leonardo Vieira Rosa, Cristiano A. Ferreira, José Luiz Barros Pena, Michael H. Picard, Charles Mady   +8 more
doaj   +1 more source

Artificial intelligence-enabled electrocardiogram screens low left ventricular ejection fraction with a degree of confidence

Digital Health, 2022
Background Artificial intelligence-enabled electrocardiogram has become a substitute tool for echocardiography in left ventricular ejection fraction estimation.
Chun-Ho Lee, Wei-Ting Liu, Yu-Sheng Lou, Chin-Sheng Lin, Wen-Hui Fang, Chia-Cheng Lee, Ching-Liang Ho, Chih-Hung Wang, Chin Lin   +8 more
doaj   +1 more source

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source