Results 131 to 140 of about 1,593,738 (428)

New Imaging-Based Tools for the Assessment of Ventricular Function in Ischemic Heart Diseases

Journal of Interdisciplinary Medicine, 2017
Ischemic heart disease morbidity and mortality are closely related to global and regional left ventricular function. The evaluation of left ventricular global function is a relevant part in the evolution of ischemic heart disease because it plays a ...
Bordi Lehel, Kovács István, Bajka Balázs, Blendea Ciprian, Rat Nora, Benedek Annabell, Suciu Zsuzsanna, Benedek Imre   +7 more
doaj   +1 more source

Relation of neurohumoral activation to clinical variables and degree of ventricular dysfunction: A report from the registry of studies of left ventricular dysfunction [PDF]

, 1994
Objectives. This study examined the relation between neurohumoral activation and severity of left ventricular dysfunction and congestive heart failure in a broad group of patients with depressed left ventricular function who were not recruited on the ...
Benedict, Claude, Bittner, Vera, Bourassa, Martial, Greenberg, Barry, Johnstone, David, Kay, Richard, Kirlin, Philip, Kohn, Robert, McIntyre, Kevin, Nicklas, John, Quinones, Miguel, Weiner, Debra, Yusuf, Salim   +12 more
core   +2 more sources

Results of coronary artery surgery in patients with poor left ventricular function (CASS).

Circulation, 1983
We identified 420 medically treated and 231 surgically treated patients (coronary graft plus myocardial surgery in 30%) who had severe left ventricular dysfunction manifest by an ejection fraction below 0.36 and markedly abnormal wall motion.
Edwin L. Alderman, Lloyd D. Fisher, P. Litwin, George C. Kaiser, William O. Myers, Charles Maynard, Frederick Levine, Michael Schloss   +7 more
semanticscholar   +1 more source

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

Importance of obesity, race and age to the cardiac structural and functional effects of hypertension [PDF]

, 1994
Objectives. The purpose of this study was to determine the effects of obesity and its interaction with age, race and the magnitude of blood pressure elevation in a large cohort of patients with mild to moderate hypertension and a high prevalence of left ...
Gottdiener, John S., Hamburger, Robert J., Henderson, William G., Massie, Barry M., Materson, Barry J., Notargiacomo, Alpo, Reda, Domenic J., Williams, David W.   +7 more
core   +1 more source

Advances in Symbiotic Bioabsorbable Devices

Advanced Science, EarlyView.
This review focuses on recent advances in bioabsorbable devices. This review concludes innovation at the material, device, and system levels, the significant advances toward biomedical applications. This review discusses and highlights the challenges and trends in symbiotic bioresorbable electronics, and provides a new direction for the development of ...
Chang Zhu, Engui Wang, Zhou Li, Han Ouyang   +3 more
wiley   +1 more source

Injectable pH Responsive Conductive Hydrogel for Intelligent Delivery of Metformin and Exosomes to Enhance Cardiac Repair after Myocardial Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Injectable pH responsive conductive hydrogel for intelligent delivery of metformin and exosomes to alleviate myocardial ischemia‐reperfusion injury. The hydrogel responds to the weakly acidic microenvironment of ischemic injury and can significantly reduce the production of intracellular ROS and enhance cardiac conduction, thereby resisting apoptosis ...
Nianlan Cheng, Qiao Luo, Yongqing Yang, Ni Shao, Tianqi Nie, Xiujiao Deng, Jifeng Chen, Siqi Zhang, Yanyu Huang, Kuan Hu, Liangping Luo, Zeyu Xiao   +11 more
wiley   +1 more source

On in-silico estimation of left ventricular end-diastolic pressure from cardiac strains [PDF]

2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1-4
Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic measure in LVDD patients, traditional invasive methods of measuring LVEDP present risks and limitations ...
arxiv   +1 more source

PRMT1 Ablation in Endothelial Cells Causes Endothelial Dysfunction and Aggravates COPD Attributable to Dysregulated NF‐κB Signaling

Advanced Science, EarlyView.
This study investigates the role of protein arginine methyltransferase 1 (PRMT1) in endothelial cells (ECs) in chronic obstructive pulmonary disease (COPD). Mice with endothelial‐specific PRMT1 deletion develop pulmonary hemorrhage, inflammation, and apoptosis, driven by excessive nuclear factor kappa B activation.
Thi Thuy Vy Tran, Yideul Jeong, Suwoo Kim, Ji Eun Yeom, Jinwoo Lee, Wonhwa Lee, Gyu‐Un Bae, Jong‐Sun Kang   +7 more
wiley   +1 more source

Effect of prolonged space flight on cardiac function and dimensions [PDF]

Echocardiographic studies were performed preflight 5 days before launch and on recovery day and 1, 2, 4, 11, 31 and 68 days postflight. From these echocardiograms measurements were made.
Epstein, S. E., Goldstein, R. E., Griffith, J. M., Henry, W. L., Redwood, D. R.   +4 more
core   +1 more source