Results 131 to 140 of about 329,876 (261)

Evaluating left ventricular function and myocardial fibrosis in hypertrophic obstructive cardiomyopathy with corrected myocardial work. [PDF]

Echo Res Pract
Zhang X, Fang L, Xie Y, Li Y, Li H, Liu M, Sun C, Yang Y, Zhang R, Xu J, Wang J, Zhang L, Lv Q, Chen S, Wu W, Xie M.   +15 more
europepmc   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Renal denervation attenuates cardiac fibrosis and improves left ventricular function in rats with myocardial infarction. [PDF]

Sci Rep
Therre M, Hohl M, Aghagolzadeh P, Selejan SR, Lauder L, Tokcan M, Markwirth P, Engler H, Hübner U, Müller A, Huynh AKD, Kahles F, Konstandin M, Böhm M, Mahfoud F.   +14 more
europepmc   +1 more source

Facile Fabrication of Low‐Impedance, Highly Conformal Epidermal Electrodes Based on Laser‐Induced Graphene–Silver Nanocomposites

Advanced Science, EarlyView.
A facile laser‐induced graphene–silver nanocomposite strategy enables ultrathin epidermal electrodes with low impedance, high conductivity, and excellent mechanical robustness. The porous LIG–Ag conductive network mechanically interlocked with SEBS provides stable, motion‐resistant biopotential monitoring, enabling high‐fidelity ECG, EMG, and EEG ...
Jiuqiang Li, Senhao Zhang, Kai Guo, Donghai Qiu, Juzhong Zhang, Hongbo Yang, Huanyu Cheng   +6 more
wiley   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

Advanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu, Kaicheng Deng, Zhang Zhang, Qirui Wang, Weijing Gao, Liyin Shen, Lei Zhang, Wenting Hu, Yang Zhu, Zhengwei Mao, Tanchen Ren   +10 more
wiley   +1 more source

Clinically Proven Cardiac Sarcoidosis Presenting as Recurrent Ventricular Tachycardia With Severely Reduced Left Ventricular Function: A Case Report. [PDF]

Cureus
Patel Y, Patel R.
europepmc   +1 more source

Dual‐Mode Nanoporous SiO2 Memristors with Coexisting Volatile and Nonvolatile Dynamics for Reservoir Computing

Advanced Science, EarlyView.
A nanoporous SiO2 memristor enabling reconfigurable volatile and non‐volatile switching within a single device is demonstrated. The dual‐mode functionality supports both physical reservoir dynamics and synaptic weight storage, allowing unified hardware implementation of reservoir computing for temporal information processing, including image and ...
Bohao Ding, Tongjun Zhang, Li Shao, Nikolay Zhelev, Andrew L. Hector, Ruomeng Huang   +5 more
wiley   +1 more source

Gender differences in asymptomatic hyperuricemia's effects on left ventricular function and remodeling in hypertension: insights from cardiac MRI. [PDF]

BMC Cardiovasc Disord
Yan WF, Li XM, Gao Y, Jiang L, Xu R, Yu SQ, Li JK, Li Y, Wang J, Yang ZG.   +9 more
europepmc   +1 more source

The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly

Advanced Science, EarlyView.
Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie, Sibing Yi, Xinle Lin, Shen Zhang, Weili Wang, Shimin Yuan, Lanlan Meng, Yong Li, Chen Tan, Chunjia Wei, Yanyan Yu, Yaoqiong Liang, Huan Zhang, Liang Hu, Guangxiu Lu, Wenbin He, Qianjun Zhang, Juan Du, Ge Lin, Chaofeng Tu, Yue‐Qiu Tan   +20 more
wiley   +1 more source

Macrophage Cluster of Differentiation 163 promotes post-infarction cardiac repair and preserves left ventricular function via osteopontin. [PDF]

Clin Transl Med
Chen J, Chen L, Huang W, Wang G, Wang L, Mei W, Ni W, Liu Y, Ding L, Ge X, Li Z, Yu J, Huang S, Lin J, Chen Y, Cai B, Zhang P, Dai C, Liu B.   +18 more
europepmc   +1 more source