Results 151 to 160 of about 1,593,738 (428)
Advanced Science, EarlyView.This study reveals a novel crosstalk between hepatic SREBP2‐mediated cholesterol biosynthesis pathway and peripheral lipoprotein lipase‐mediated lipolysis pathway in the regulation of systemic lipid metabolism. Notably, the lipid‐lowering effects of SREBP2 inhibition are independent of a functional LDL receptor, highlighting the potential of acute ...
Yifan Wang +13 more
wiley +1 more source
AGING MEDICINE, Volume 5, Issue 4, Page 257-263, December 2022., 2022 The main finding in our study is that Clinical Frailty Scale‐defined frailty status was predictive of 1‐year post‐interventional mortality after left ventricular assist device implantation. Abstract Objectives Heart failure impacts patients’ functional capabilities, ultimately leading to frailty.
Temitope Ajibawo +3 more
wiley +1 more source
Automated and Interpretable Patient ECG Profiles for Disease Detection, Tracking, and Discovery [PDF]
arXiv, 2018 The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power, innovations in machine learning algorithms, and availability of large-scale digitized ECG data would enable extending ...
arxiv
Advanced Science, EarlyView.In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang +10 more
wiley +1 more source
Myocardial Function and Left Ventricular Volumes in Acquired Valvular Insufficiency [PDF]
, 1965 Graham Miller +2 more
openalex +1 more source
A Wavelet Approach for the Estimation of Left Ventricular Early Filling Wave Propagation Velocity from Color-M-Mode Echocardiograms [PDF]
arXiv, 2019 Objective: This work evaluates a new approach for calculating the left-ventricular (LV) early filling propagation velocity (VP) from color M-Mode (CMM) echocardiograms using wavelet analysis. Unlike current approaches, the method requires no assumptions, user inputs, or heuristic conventions.
arxiv
Advanced Science, EarlyView.Parkinson's disease (PD) progression is aggravated by disrupted inter‐organelle contacts, which are influenced by mechanical forces. NanoMassage, 200 nm PEGylated black phosphorus nanosheets, deliver targeted mechanical stimulation to neural cells.
Tianqi Li +12 more
wiley +1 more source
American Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023 Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter +14 more
wiley +1 more source
Left ventricular function in experimental aorto-caval fistula with circulatory congestion and fluid retention [PDF]
, 1968 Roger R. Taylor +2 more
openalex +1 more source
A novel quantitative indicator of the left ventricular contraction based on volume changes of the left ventricular myocardial segments [PDF]
arXiv, 2018 Ejection fraction (EF) is commonly measured by echocardiography, by dividing the volume ejected by the heart (stroke volume) by the volume of the filled heart (end-diastolic volume). Utilizing volume changes of left myocardial segments per a cardiac cycle, physical laws and mathematical equations specific echocardiographic data, this paper serves to ...
arxiv