Results 221 to 230 of about 2,971,220 (284)
Experimental Physiology, EarlyView.Abstract The clinical assessment of cardiovascular function during exercise using stress echocardiography is essential for accurate cardiac diagnosis. However, normal limitations of cardiac deformation responses to increasing physical exertion remain poorly understood.
Fabian Spahiu +4 more
wiley +1 more source
Clearance of p16‐positive cardiac cells improves age‐related cardiac remodeling in mice
Experimental Physiology, EarlyView.Abstract Senescent cells are characterized by expression of markers like p16 and secretion of profibrotic and proinflammatory factors. The role of cellular senescence in age‐related cardiac remodeling and dysfunction is incompletely understood. This study aimed to: (i) evaluate the effect of p16‐ positive cell clearance on cardiac function and ...
Mozhdeh Mehdizadeh +12 more
wiley +1 more source
Experimental Physiology, EarlyView.Abstract High‐intensity endurance exercise induces myocardial remodelling as an adaptive response to sustained volume overload, but excessive cumulative training might also favour deleterious cardiac remodelling, including atrial fibrosis. Whether acute marathon running engages circulating fibrosis‐related biomarkers and whether these biomarkers track ...
Felipe Contreras‐Briceño +6 more
wiley +1 more source
Factors Related with Both Epicardial Fat Thickness and Left Ventricular Geometry. [PDF]
Acta Cardiol Sin, 2019 Ziya Şener Y, Okşul M, Hekimsoy V.
europepmc +1 more source
Experimental Physiology, EarlyView.Abstract The vascular sympathetic baroreflex is critical for stabilising blood pressure. A notable feature of this reflex is hysteresis, a directional asymmetry in responsiveness during rising versus falling pressure that is evident in young adults but attenuated in older age.
Guto Wyn Hughes +5 more
wiley +1 more source
The comparison of the impact of arterial stiffness and central pressure on left ventricular geometry and diastolic function. [PDF]
Clin Hypertens, 2019 Kim HL +5 more
europepmc +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend The results from this study show that maximal cardiac output, stroke volume and leg blood flow are similar between highly trained females and males after normalisation to lean body mass (LBM). However, the 10% higher haemoglobin concentration ([Hb]) and arterial O2 content in males result in higher systemic and leg O2 delivery ...
Øyvind Skattebo +11 more
wiley +1 more source
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
Left ventricular geometry and contraction in patients with right ventricular overload
Shinzo, 1985 Miyamori, Ryoko +7 more
openaire +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas +3 more
wiley +1 more source