Results 241 to 250 of about 2,971,220 (284)

When NCX switches sides: Experimental and computational insights into Ca2+ regulation in the heart

The Journal of Physiology, EarlyView.
Abstract figure legend Due to its presence inside the dyadic cleft, Na+/Ca2+ exchanger (NCX) builds a functional unit together with L‐type calcium channels and ryanodine receptors in the dyadic cleft. NCX acts bidirectionally (forward and reverse mode) dependent on extracellular calcium ([Ca2+]o) and sodium ([Na+]o) concentrations and the membrane ...
Wilhelm Neubert, Judith Hüttemeister, Paulina Sander, Nagaiah Chamakuri, Felix Hohendanner, Martin Falcke, Frank R. Heinzel   +6 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

High‐throughput, high‐fidelity reconstruction of whole mouse‐heart cytoarchitecture at cellular scale

The Journal of Physiology, EarlyView.
Abstract figure legend Experimental workflow of the dual‐camera light‐sheet microscope (dual‐mesoSPIM) pipeline. Intact adult mouse hearts undergo CUBIC‐based delipidation and refractive‐index matching, rendering the whole organ optically transparent (left).
Francesco Giardini, Chiara Palandri, Sofia Botti, Camilla Olianti, Paolo Mele, Niccolò Ballerini, Roberto Piersanti, Mauro Giacca, Peter Kohl, Callum M. Zgierski‐Johnston, Elisabetta Cerbai, Francesco Regazzoni, Leonardo Sacconi   +12 more
wiley   +1 more source

Relation of left ventricular systolic and diastolic function to left ventricular geometry in hypertensive patients

Kardiologia Polska, 2004
Orzeszko, Jacek, Mazurek, Walentyna
openaire  

Disturbed Glucose Metabolism and Left Ventricular Geometry in the General Population [PDF]

Journal of Clinical Medicine, 2021
Volker H Schmitt, Thomas Münzel, Omar Hahad   +2 more
exaly   +2 more sources

Extracellular Superoxide Dismutase Is Associated With Left Ventricular Geometry and Heart Failure in Patients With Cardiovascular Disease [PDF]

Journal of the American Heart Association, 2020
Min Xia, Jingmeng Ju, Wang Xiaohui
exaly   +2 more sources

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Left ventricular geometry after endoventriculoplasty

European Journal of Cardio-Thoracic Surgery, 1993
From 1988 to 1992, 65 patients underwent endoventriculoplasty (EVP) for anteroapical left ventricular aneurysm. The operative mortality was 4.6%, and 9.2% needed intraaortic balloon counterpulsation (IABP). Forty-three patients were restudied by ventriculography and the preoperative and postoperative silhouettes were analyzed by means of a special ...
M, Salati, P, Di Biasi, A, Pajè, C, Santoli   +3 more
openaire   +2 more sources

Left Ventricular Geometry and Survival in Patients With Normal Left Ventricular Ejection Fraction

The American Journal of Cardiology, 2006
In hypertensive populations, left ventricular (LV) geometry, which is characterized by hypertrophy, predicts cardiovascular outcome. The left ventricle can also alter its shape by concentric remodeling (CR) in the absence of LV hypertrophy, a feature that is detected by echocardiography. This study assessed the prevalence and prognostic significance of
Milani, R. V., Lavie, C. J., Mehra, M. R., Ventura, H. O., Kurtz, J. D., Messerli, F. H.   +5 more
openaire   +5 more sources

Left ventricular geometry and risk of incident hypertension

Heart, 2019
Objective Left ventricular (LV) geometry change is an independent predictor for cardiovascular disease. However, data are equivocal on the association of echocardiographic parameters of LV geometry with incident hypertension.
Sung Keun Park, Ju Young Jung, Jeong Gyu Kang, Pil-Wook Chung, Chang-Mo Oh   +4 more
openaire   +2 more sources

Prognostic value of left ventricular mass and geometry in systemic hypertension with left ventricular hypertrophy

The American Journal of Cardiology, 1996
To determine the independent prognostic significance of left ventricular (LV) mass and geometry (concentric vs eccentric pattern) in hypertensive subjects with LV hypertrophy at echocardiography, 274 subjects were followed for up to 8.7 years (mean 3.2).
P. Verdecchia, SCHILLACI, Giuseppe, C. Borgioni, A. Ciucci, R. Gattobigio, I. Zampi, A. Santucci, C. Santucci, REBOLDI, Gianpaolo, C. Porcellati   +9 more
openaire   +3 more sources