Results 101 to 110 of about 587,865 (399)

The Impact of Standard Ablation Strategies for Atrial Fibrillation on Cardiovascular Performance in a Four-chamber Heart Model [PDF]

arXiv, 2022
Atrial fibrillation is one of the most frequent cardiac arrhythmias in the industrialized world and ablation therapy is the method of choice for many patients. However, ablation scars alter the electrophysiological activation and the mechanical behavior of the affected atria.
arxiv  

Impaired Ca2+-handling in HIF-1α+/− mice as a consequence of pressure overload [PDF]

, 2009
The hypoxia-inducible factor (HIF)-1 is critically involved in the cellular adaptation to a decrease in oxygen availability. The influence of HIF-1α for the development of cardiac hypertrophy and cardiac function that occurs in response to sustained ...
A Robinson, A Siddiq, Adam G. Rokita, AK Neumann, Anke Zieseniss, AY Yu, D Tirziu, DM Katschinski, Dörthe M. Katschinski, G Kissling, G Loor, Gerhard Breves, GL Semenza, GL Semenza, H Liu, H Witt, Harald Kögler, HE Ryan, HH Marti, J Krishnan, J Krishnan, JR Resar, Jörg Wilting, Karl Toischer, Katrin Schäfer, Lars S. Maier, LS Maier, M Huang, M Ivan, M Kido, M Sano, MA Hlatky, Monique Silter, N Masson, O Baranova, P Fraisl, P Hill, P Jaakkola, PH Maxwell, RH Wenger, T Eckle, WG Kaelin Jr, WM Bernhardt, WM Bernhardt, Y Huang, Y Jiang, Z Cai   +46 more
core   +2 more sources

The Gene Polymorphism of Angiotensin-Converting Enzyme Intron Deletion and Angiotensin-Converting Enzyme G2350A in Patients With Left Ventricular Hypertrophy: A Meta-analysis

Indian Heart Journal, 2019
Objectives: The aim of the study was to evaluate the correlation between left ventricular hypertrophy and the gene polymorphism of angiotensin-converting enzyme (ACE) intron deletion (I/D) and ACE G2350A.
Jonny Karunia Fajar, Budi Susetio Pikir, Erdo Puncak Sidarta, Putu Nina Berlinda Saka, Rizal Rahmanda Akbar, Teuku Heriansyah   +5 more
doaj  

Prenatal Brain Abnormalities in Sodium‐Dependent Multivitamin Transporter Deficiency

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT In treatable neurometabolic disorders, early diagnosis and prompt initiation of treatment are key to improved survival and outcomes. Biallelic variants in SLC5A6 cause sodium‐dependent multivitamin transporter deficiency (OMIM # 618973), which is treatable with high‐dose pantothenic acid, biotin, and alpha lipoic acid.
Eri Ogawa, Kenjiro Kosaki, Toshiki Takenouchi   +2 more
wiley   +1 more source

On in-silico estimation of left ventricular end-diastolic pressure from cardiac strains [PDF]

2024 46th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), pp. 1-4
Left ventricular diastolic dysfunction (LVDD) is a group of diseases that adversely affect the passive phase of the cardiac cycle and can lead to heart failure. While left ventricular end-diastolic pressure (LVEDP) is a valuable prognostic measure in LVDD patients, traditional invasive methods of measuring LVEDP present risks and limitations ...
arxiv   +1 more source

Left ventricular hypertrophy: pathogenesis, detection, and prognosis.

Circulation, 2000
When the heart faces a hemodynamic burden, it can do the following to compensate: (1) use the Frank-Starling mechanism to increase crossbridge formation; (2) augment muscle mass to bear the extra load; and (3) recruit neurohormonal mechanisms to increase
B. Lorell, B. Carabello
semanticscholar   +1 more source

Screening for Fabry Disease in Left Ventricular Hypertrophy: Documentation of a Novel Mutation

Arquivos Brasileiros de Cardiologia, 2015
Background: Fabry disease is a lysosomal storage disease caused by enzyme α-galactosidase A deficiency as a result of mutations in the GLA gene. Cardiac involvement is characterized by progressive left ventricular hypertrophy.
Ana Baptista, Pedro Magalhães, Sílvia Leão, Sofia Carvalho, Pedro Mateus, Ilídio Moreira   +5 more
doaj   +1 more source

Metformin Improves Cardiac Metabolism and Function, and Prevents Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background In spontaneously hypertensive rats (SHR) we observed profound myocardial metabolic changes during early hypertension before development of cardiac dysfunction and left ventricular hypertrophy.
Jie Li, Krzysztof Minćzuk, James C. Massey, Nancy L. Howell, R. Jack Roy, Soumen Paul, James T. Patrie, Christopher M. Kramer, Frederick H. Epstein, Robert M. Carey, Heinrich Taegtmeyer, Susanna R. Keller, Bijoy K. Kundu   +12 more
doaj   +1 more source

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel, Julie McLaughlin, Marta Frigeni   +2 more
wiley   +1 more source

Characterization of Left Ventricular Hypertrophy via Fractional Derivatives [PDF]

arXiv, 2017
In this paper, we have used the concepts of the fractional derivative of rough curves to characterize ECG of LVH patients and compared the results with normal ECGs. In mathematical language, an ECG is a rough curve having Q, R, S points as non-differentiable points where classical derivatives do not exist but fractional derivatives exist.
arxiv