Results 111 to 120 of about 585,525 (398)

Metformin Improves Cardiac Metabolism and Function, and Prevents Left Ventricular Hypertrophy in Spontaneously Hypertensive Rats

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background In spontaneously hypertensive rats (SHR) we observed profound myocardial metabolic changes during early hypertension before development of cardiac dysfunction and left ventricular hypertrophy.
Jie Li   +12 more
doaj   +1 more source

Relationship between Systolic Arterial Pressure and Heart Mass in the Rat [PDF]

open access: yes, 1993
This study describes the relationship between left ventricular mass and systolic arterial pressure (SAP) in normotensive and hypertensive rats. The genetically hypertensive rats (SHR) were stratified according to their SAP values in to hypertensive (SHRH)
Grassi de Gende, Ángela
core   +1 more source

Impact of Elevated Preprocedural Left Ventricular Filling Pressure on Prognosis of Mild Paravalvular Regurgitation Following Transcatheter Aortic Valve Replacement

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Paravalvular regurgitation (PVR) following transcatheter aortic valve replacement (TAVR) is a complication linked to poor outcomes. The prognostic impact of mild PVR, particularly in patients with elevated preprocedural left ventricular (LV) filling pressure, remains uncertain.
Shumpei Kosugi   +12 more
wiley   +1 more source

Mutation update for the ACTN2 gene

open access: yesHuman Mutation, Volume 43, Issue 12, Page 1745-1756, December 2022., 2022
Abstract ACTN2 encodes alpha‐actinin‐2, a protein expressed in human cardiac and skeletal muscle. The protein, located in the sarcomere Z‐disk, functions as a link between the anti‐parallel actin filaments. This important structural protein also binds N‐terminal titins, and thus contributes to sarcomere stability.
Johanna Ranta‐aho   +13 more
wiley   +1 more source

Diabetes, gender, and left ventricular structure in African-Americans: the atherosclerosis risk in communities study

open access: yesCardiovascular Ultrasound, 2006
Background Cardiovascular risk associated with diabetes may be partially attributed to left ventricular structural abnormalities. However, the relations between left ventricular structure and diabetes have not been extensively studied in African ...
Liebson Philip R   +6 more
doaj   +1 more source

Automated and Interpretable Patient ECG Profiles for Disease Detection, Tracking, and Discovery [PDF]

open access: yesarXiv, 2018
The electrocardiogram or ECG has been in use for over 100 years and remains the most widely performed diagnostic test to characterize cardiac structure and electrical activity. We hypothesized that parallel advances in computing power, innovations in machine learning algorithms, and availability of large-scale digitized ECG data would enable extending ...
arxiv  

Left Ventricular Hypertrophy in Obese Hypertensives: Is It Really Eccentric? (An Echocardiographic Study) [PDF]

open access: yes, 2000
In order to study left ventricular hypertrophy patterns in obese hypertensives, we examined 132 patients with essential hypertension by 2D, M-mode and Doppler echocardiography.
A. Šmalcelj   +3 more
core   +1 more source

Influence of Patern and Degree of Left Ventricular Hypertrophy on Cardiac Arrhythmias [PDF]

open access: yes, 2012
A large number of clinical and epidemiological studies [1,2] have reported a correlation between the mass increase of the left ventricle (LV) and the risk of disease or death.
Juraj Kunisek
core   +1 more source

ENPP1 deficiency: A clinical update on the relevance of individual variants using a locus‐specific patient database

open access: yesHuman Mutation, Volume 43, Issue 12, Page 1673-1705, December 2022., 2022
Abstract Loss‐of‐function variants in the ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1) cause ENPP1 Deficiency, a rare disorder characterized by pathological calcification, neointimal proliferation, and impaired bone mineralization. The consequence of ENPP1 Deficiency is a broad range of age dependent symptoms and morbidities
Stephanie A. Mercurio   +8 more
wiley   +1 more source

Non-invasive electrical markers in patients with left ventricular hypertrophy.

open access: yesRevista Cubana de Cardiología y Cirugía Cardiovascular, 2011
Introduction The left ventricular hypertrophy is related with the genesis of ventricular arrhythmiasand sudden death. Depending of the cause, different histologycalmodifications that generate different arrhythmogenic substrates, takesplace.
Nadia Sánchez Torres   +5 more
doaj  

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