Three-dimensional Cardiovascular Imaging-Genetics: A Mass Univariate Framework [PDF]
, 2017 MOTIVATION: Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained. Conventional phenotyping relies on manual calculation of LV mass and wall thickness, but advanced cardiac image analysis presents an opportunity for high-throughput mapping of genotype-phenotype ...
arxiv +1 more source
Indicators of left ventricle hypertrophy in patients with arterial hypertension combined with obesity and their interconnection with polymorphism of Lys198Asn genе of endothelin-1 [PDF]
, 2020 Одним із незалежних факторів розвитку серцево-судинних ускладнень є гіпертрофія лівого шлуночка. З кожним роком з’являється все більше публікацій, які доводять, що ця проблема є генетично обумовленою.Одним из независимых факторов развития сердечно ...
Chernatska, Olha Mykolaivna +11 more
core +1 more source
[OP.2D.05] RELATIONSHIP OF OXIDATIVE STRESS WITH CARDIAC HYPERTROPHY IN HYPERTENSIVE PATIENTS [PDF]
, 2016 OBJECTIVE: Left ventricular hypertrophy is common in hypertensive patients. In these subjects increased oxidative stress has been observed. Our aim was to evaluate the association of biomarkers of both oxidative stress and inflammation with markers of ...
Altieri, D. +6 more
core +1 more source
Advanced Science, EarlyView.In KLF1‐on (neonatal and Klf1 overexpression hearts) models, KLF1 regulates Wnt/β‐catenin signaling pathway and the expression of cell proliferation‐related genes via transcriptional and epigenetic mechanisms, which induces cardiomyocyte proliferation and cardiac regeneration in mice after myocardial infarction.
Yanglin Hao +19 more
wiley +1 more source
مجلة كلية الطب, 2010 Background: Left ventricular hypertrophy and diastolic dysfunction are considered to be an important risk factor for cardiovascular morbidity and mortality in asymptomatic hypertensive patients.
Salam A. Mahdi +2 more
doaj +1 more source
Electrocardiogram and vectorcardiogram in left ventricular hypertrophy of valvular heart disease [PDF]
, 1964 Several systems of criteria have been offered for the electrocardiographic diagnosis of left ventricular hypertrophy (1,6,7,8,11,13,14,16). None is completely satisfactory since one system errs in including too many normals and at the other end of the ...
Nuhoglu, Remzi
core +1 more source
Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
Advanced Science, EarlyView.The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan +16 more
wiley +1 more source
PREVALENCE OF LEFT VENTRICULAR HYPERTROPHY IN NEWLY DIAGNOSED HYPERTENSIVE PATIENTS
Pakistan Armed Forces Medical Journal, 2020 Objective: To detect frequency of left ventricular hypertrophy in patients with newly diagnosed hypertension. Study Design: Cross sectional study. Place and Duration of Study: Out patient and inpatient, Department of Medicine of Combined Military ...
Umair Masood +5 more
doaj
The electrocardiogram of combined ventricular hypertrophy of the heart [PDF]
, 2019 Combined ventricular hypertrophy was the commonest finding at autopsy in cases studied by cardiac partitioning. A large number of electrocardiographic deflections reflected left or right ventricular hypertrophy in cases with combined ventricular ...
Palmhert, R., van Lingen, B.
core +1 more source
Association of carotid atherosclerosis and left ventricular hypertrophy. [PDF]
, 1995 Objectives. This study was undertaken to determine the prevalence of carotid atherosclerosis in a large group of asymptomatic hypertensive and normotensive adults and to examine its relation to the presence of left ventricular hypertrophy.Background ...
Deverexu, R. B. +4 more
core +1 more source