Results 121 to 130 of about 9,025,884 (293)

Microalbuminuria as an indicator for LVH severity in patients with primary hypertension

Journal of Family Medicine and Primary Care
Background: Hypertension is among the most complex global public health concerns. Hypertension and kidney diseases share a strong correlation. The existence of microalbuminuria signifies early renal impairment.
Govind Tripathi, Shobhit Shah, Akhilesh K. Singh, Akshyaya Pradhan   +3 more
doaj   +1 more source

Left ventricular structure and function in sedentary and physically active subjects with left ventricular hypertrophy (the LIFE Study)

, 2005
Patients with left ventricular hypertrophy had higher heart rates, left ventricular mass, and left atrial size independent of gender, blood pressure, or body mass index than physically active ...
Olofsson, M., Gerdts, E., Papademetriou, V., Devereux, Richard B, Dahlöf, Björn,, Papademetriou, Vasilios, Gerdts, Eva, Boman, Kurt,, Boman, K., Nieminen, Markku S, Nieminen, M. S., Wachtell, Kristian, Devereux, R. B., Olofsson, Mona, Dahlöf, Björn, Wachtell, K.   +15 more
core   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Hypertension and cardiac damage in pheochromocytoma and paraganglioma patients: a large-scale single-center cohort study

BMC Cardiovascular Disorders
Background Hypertension (HT) is one of the most common manifestations in patients with catecholamine-secreting neuroendocrine tumors. Although the cardiovascular manifestations of these tumors have been described, there have been no large-scale ...
Yang Yu, Chuyun Chen, Lei Meng, Wencong Han, Yan Zhang, Zheng Zhang, Ying Yang   +6 more
doaj   +1 more source

The relationship between aortic calcification, mean femoral Z-scores and left ventricular mass index.

, 2013
Both low mean femoral Z-score (below zero) and presence of aortic calcification were significantly associated with increased left ventricular mass index ...
Richard P. Steeds (319166), Jonathan N. Townend (319167), Colin D. Chue (136552), William E. Moody (319163), Nicola J. Crabtree (319161), Nicola C. Edwards (319164), Daniel Zehnder (291721), Nadezhda A. Wall (319159), Charles J. Ferro (319168)   +8 more
core   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source

Tri-ponderal mass index and left ventricular hypertrophy in a cohort of caucasian children and adolescents with obesity

Italian Journal of Pediatrics
Background Pediatric obesity is a global emerging burden for society; among its health-related consequences there are hypertension (HTN) and left ventricular hypertrophy (LVH).
Sara Vizzuso, Alberico Del Torto, Giulia Fiore, Stefano Carugo, Gianvincenzo Zuccotti, Elvira Verduci   +5 more
doaj   +1 more source

Neuron‐Derived Vesicular circMagi1 Restrains Vascular Repair After Ischemic Stroke by Promoting TRIM65‐Mediated ANXA2 Degradation

Advanced Science, EarlyView.
After ischemic stroke, injured neurons transfer circMagi1 to endothelial cells through extracellular vesicles. Within endothelial cells, circMagi1 binds ANXA2 and enhances its engagement with TRIM65, promoting ANXA2 ubiquitination and proteasomal degradation to constrain angiogenic repair.
Youkun Bi, Qun Liu, Baohua Zou, Wenyuan Wang, Xinlong Qiao, Lin Gao, Chaoxu Miao, Ningning Huang, Shuqing Tang, Rui Guo, Changqing Zeng, Ce Jia, Yuanchao Xue, Xuejun Guo, Jianjun Chen, Huiwen Wang, Guangju Ji   +16 more
wiley   +1 more source

Effect of Body Mass Index on Left Ventricular Diastolic Function [PDF]

, 2018
Introduction: Overweight and obese persons are at increased risk for heart failure. A direct effect of isolated obesity on cardiac function is not well established.OBJECTIVE: To assess the independent effect of increased body mass index on the left ...
Dr.Ahmed N. Rgeeb, Dr. Ammar Emad Ali/ Dr.MohammedH.Al-Meshhadani/
core