Results 51 to 60 of about 27,658 (219)

ELABELA Targets Mitochondria to Modulate Heart Development

Advanced Science, EarlyView.
The role of peptide ELABELA (ELA) in cardiomyocyte apoptosis and congenital heart disease (CHD) is unclear. ELA deficiency caused cardiomyocyte apoptosis and CHD. A novel ELA‐APJ‐AKT‐BCL2/BAX axis in regulating mitochondrial function and contributing to CHD pathogenesis was established.
Jian Wang, Qingjie Wang, Zhikang Xu, Shuang Zhou, Yue Zhou, Junjie Yang, Lingfeng Tong, Zhuo Meng, Mei Yang, Wen Zhao, Tie Yang, Hualin Wang, Jun Zhang, Rubin Tan, Lei Wang, Yuqiang Huang, Bin Zhou, Sun Chen, Bing Zhang, Jinxiang Yuan, Jianyuan Zhao, Alex F. Chen, Kun Sun   +22 more
wiley   +1 more source

Giant Cardiac Rhabdomyoma with Mixed Atrial Tachycardia and Nonsustained Ventricular Tachycardia in a Newborn with Tuberous Sclerosis

The Ewha Medical Journal, 2022
Cardiac rhabdomyomas are typically presented in the tuberous sclerosis. Although benign and often associated with spontaneous regression, in rare circumstances huge mass size and critical location can lead to heart failure, ventricular outflow tract ...
Kyung Hee Kim, Ji-Eun Ban
doaj   +1 more source

Conformable Microelectrode Arrays Integrated with a Scoop‐Shaped Slide‐Well for Dynamic Electrophysiological Profiling of Patient‐Derived Cardiac Organoids

Advanced Science, EarlyView.
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim, Jeonghwa Jeong, Gyeonghwa Heo, Young Woo Kwon, Jeongha Lee, Yoon Ji Jeong, Gyu Tae Park, Seongdo Jeong, Ki Won Hwang, Murim Choi, Jinhong Shin, Suck Won Hong, Jae Ho Kim   +12 more
wiley   +1 more source

A One Health Approach to Hypertrophic Cardiomyopathy. [PDF]

, 2017
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease in humans and results in significant morbidity and mortality. Research over the past 25 years has contributed enormous insight into this inherited disease particularly in the ...
Stern, Joshua A, Ueda, Yu
core   +1 more source

Initial results of combined anterior mitral leaflet extension and myectomy in patients with obstructive hypertrophic cardiomyopathy [PDF]

, 1996
Objectives. The purpose of this study was to describe the clinical and functional results of combined anterior mitral leaflet extension and myectomy in patients with hypertrophic obstructive cardiomyopathy. Background.
Boersma, H. (Eric), Cate, F.J. (Folkert) ten, Herwerden, L.A. (Lex) van, Kofflard, M.J.M. (Marcel), Ruygrok, P.N. (Peter), Taams, M.A. (Meindert), Waldstein, D.J.   +6 more
core   +1 more source

Co‐Occurring Non‐Cardiac Congenital Anomalies Among Cases With Congenital Heart Defects

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Cases with congenital heart defects (CHD) often have other associated anomalies. The aim of this investigation was to assess the prevalence and the types of co‐occurring anomalies in CHD in a well‐defined population. The anomalies co‐occurring with CHD were ascertained in all live births, stillbirths and terminations of pregnancy for fetal ...
Claude Stoll, Yves Alembik, Marie‐Paule Roth   +2 more
wiley   +1 more source

Anaesthetic management of a patient with hypertrophic obstructive cardiomyopathy posted for emergency lower segment caesarean section

Journal of Obstetric Anaesthesia and Critical Care, 2017
Hypertrophic cardiomyopathy is characterised by asymmetric hypertrophy of the interventricular septum causing intermittent obstruction of the left ventricular outflow tract.
Pradnya M Bhalerao, Pritam B Adsule, Radhika M Marathe   +2 more
doaj   +1 more source

Unexpected systolic anterior motion of the mitral valve-related hypoxemia during transurethral resection of the prostate under spinal anesthesia: a case report

BMC Anesthesiology, 2022
Background Dynamic obstruction of the left ventricular outflow tract resulting from systolic anterior motion of the mitral valve can be an unexpected cause of acute and severe perioperative hypotension in noncardiac surgery.
Chien-Ju Chou, Yi-Chen Lai, Shu-Yu Ou, Chen-Hsiu Chen   +3 more
doaj   +1 more source

An Early Holiday Surprise: Cholecystitis Wrapped in Takotsubo Cardiomyopathy [PDF]

, 2020
This is a novel case report of a 44-year-old woman who presented to the emergency department with epigastric pain wrapping around to her back. She had no risk factors for cardiac disease, but her initial electrocardiogram (ECG) showed a Wellens syndrome ...
Gould, Kevin, Miller, Stephen, Moll, Joel   +2 more
core  

Myocardial energy depletion and dynamic systolic dysfunction in hypertrophic cardiomyopathy [PDF]

, 2016
Evidence indicates that anatomical and physiological phenotypes of hypertrophic cardiomyopathy (HCM) stem from genetically mediated, inefficient cardiomyocyte energy utilization, and subsequent cellular energy depletion.
A Shah, AA Geisterfer-Lowrance, AC Hoskins, BC Knollman, BJ Maron, BJ Maron, C Ferrantini, C O'Mahony, C O'Mahony, CJ Neil, CS Redwood, CW Tong, CY Ho, DG Hardie, DK Dawson, DT Lucas, DV Unverferth, E Blair, EM Green, ER Witjas-Paalberends, ER Witjas-Paalberends, F Baudenbacher, F Cecchi, F Lan, F Merante, F Pelliccia, H Ashrafian, H Ashrafian, H Ashrafian, H Watkins, HM Conklin, HP Beyerbacht, I Barac, I Olivotto, I Olivotto, J Ross, J Ross Jr, J Ross Jr, J Ross Jr., J Tardiff, JA Wagner, JE Brush Jr, JG Crilley, JO Ormerod, JR Po, Julian O. M. Ormerod, K Abozguia, K Abozguia, K Gehmlich, K Okeie, K Sakata, K Unno, L Thierfelder, M Bunse, M Mahmod, M Mahmod, M Sherrid, M Spindler, Mark V. Sherrid, Michael P. Frenneaux, ML Alves, MM Javadpour, MS Maron, MV Sherrid, MV Sherrid, MV Sherrid, MV Sherrid, N Günal, OA Breithardt, PT O'Gara, R Coppini, R Lodi, R Lodi, RC Saumarez, RH Chan, RO3rd Cannon, RO3rd Cannon, S Dass, S Huke, S Huke, S Ishiwata, S Marston, S Neubauer, S Neubauer, S Sasayama, S Singh, SA Timmer, SA Timmer, SA Timmer, SB Danik, SG Sirenko, SJ van Dijk, SS Lele, TB Levine, V Sequeira, WI Jung, Y Matsumura, Y Mishiro, YM Cha   +98 more
core   +1 more source