Results 61 to 70 of about 27,658 (219)

Optimization and verification of high‐fat diet formulation for establishing a rat model of obesity‐related precocious puberty

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We identified 45% HFD as the optimal formulation to establish a juvenile rat model of obesity‐related precocious puberty. It elicits robust phenotypic (early vaginal opening, obesity), histological (advanced ovarian development), and endocrine (elevated HPG axis hormones) alterations, with leptin‐mediated GnRH secretion as a core mechanistic driver ...
Jiayi Gong   +5 more
wiley   +1 more source

The Prevalence of Fabry Disease Among Turkish Patients with Non-Obstructive Hypertrophic Cardiomyopathy: Insights from a Screening Study

open access: yesBalkan Medical Journal, 2019
Aims: Fabry disease is an X-linked lysosomal storage disorder due to a deficiency of the α-galactosidase A enzyme. Cardiac involvement is present in over 60% of adult cases of Fabry disease.
Hasan Ali Barman   +7 more
doaj   +1 more source

Outcomes in Patients With Obstructive Hypertrophic Cardiomyopathy and Concomitant Aortic Stenosis Undergoing Surgical Myectomy and Aortic Valve Replacement

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Hypertrophic cardiomyopathy (HCM) and aortic stenosis can cause obstruction to the flow of blood out of the left ventricular outflow tract into the aorta, with obstructive HCM resulting in dynamic left ventricular outflow tract obstruction and
Milind Y. Desai   +9 more
doaj   +1 more source

Systolic ejection murmurs and the left ventricular outflow tract in boxer dogs [PDF]

open access: yes, 2007
Turbulence of various genesis in the left ventricular outflow tract (LVOT) causes systolic ejection murmurs. The prevalence of murmurs in adult boxer dogs is 50-80%, the majority of which are of low intensity.
Höglund, Katja
core  

Research progress on biomarkers of traumatic brain injury

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen   +8 more
wiley   +1 more source

Left ventricular mid-cavity obstruction: A novel cause of duct-dependent systemic circulation in a newborn

open access: yesAnnals of Pediatric Cardiology
Accessory mitral valve tissue is a rare congenital anomaly that may cause left ventricular outflow tract obstruction. This may be the first case report in a neonate, describing accessory mitral valve tissue producing a significant left ventricular ...
Salim Nasser Al-Maskari   +3 more
doaj   +1 more source

Prevalence, associated factors and management implications of left ventricular outflow tract obstruction in Takotsubo cardiomyopathy: a two-year, two-center experience [PDF]

open access: yes, 2014
Background: Some patients with Takotsubo cardiomyopathy (TTC) develop cardiogenic shock due to left ventricular outflow tract (LVOT) obstruction -there is, however, a paucity of data regarding this condition.
De Backer, Ole   +5 more
core   +2 more sources

Age and gender effects on echocardiographic and histopathological cardiac phenotypes in healthy adult mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study investigated the impact of age and sex on cardiac phenotypes in healthy adult C57BL/6J mice using echocardiography and histopathological analyses. Findings revealed that female mice demonstrated more pronounced global cardiac chamber dilation during aging.
Shuang Wen   +6 more
wiley   +1 more source

Composite valved apico-aortic conduits for left ventricular outflow obstruction.

open access: yesActa Médica Portuguesa, 1980
Problems related to the left ventricular outflow tract are not always amenable to conventional surgical methods, and in some cases may be solved with the creation of a double outlet left ventricle, using a composite rigid pyrolite left ventricular apex ...
Denton A. Cooley, John C. Norman
doaj   +1 more source

Changes in left atrial deformation in hypertrophic cardiomyopathy: Evaluation by vector velocity imaging. [PDF]

open access: yes, 2012
OBJECTIVES: Hypertrophic cardiomyopathy (HCM) represents a generalized myopathic process affecting both ventricular and atrial myocardium. We assessed the global and regional left atrial (LA) function and its relation to left ventricular (LV) mechanics ...
Badran, HM   +6 more
core   +2 more sources

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