Results 101 to 110 of about 547,971 (352)

Effects of neuregulin-1 on autonomic nervous system remodeling post-myocardial infarction in a rat model

Neural Regeneration Research, 2017
Sympathetic nerve and vagus nerve remodeling play an important part in cardiac function post-myocardial infarction (MI). Increasing evidence indicates that neuregulin-1 (NRG-1) improves cardiac function following heart failure.
Xin Lai, Liang Zhong, Hai-xia Fu, Song Dang, Xin Wang, Ning Zhang, Gao-ke Feng, Zi-qiang Liu, Xi Wang, Long Wang   +9 more
doaj   +1 more source

Transplantation of progenitor cells and regeneration enhancement in acute myocardial infarction - (TOPCARE-AMI)

, 2002
Background - Experimental studies suggest that transplantation of blood-derived or bone marrow–derived progenitor cells beneficially affects postinfarction remodeling.
Dimmeler, S, Teupe, C, Martin, H, Döbert, N, Hoelzer, D, Lehmann, R, Aicher, A, Schächinger, V, Urbich, C, Assmus, B, Britten, M, Zeiher, AM, Grünwald, F   +12 more
core   +1 more source

CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation

Advanced Science, EarlyView.
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu, Cheng Kiu Ho, Jitao Liu, Lei Cui, Yangfeng Hou, Cai Liang, Wenchu Ye, Randolph H. L. Wong, Shohei Hori, Bin Zhou, Kathy O. Lui   +10 more
wiley   +1 more source

Remote Zone Extracellular Volume and Left Ventricular Remodeling in Survivors of ST-Elevation Myocardial Infarction

HYPERTENSION, 2016
The natural history and pathophysiological significance of tissue remodeling in the myocardial remote zone after acute ST-elevation myocardial infarction (STEMI) is incompletely understood. Extracellular volume (ECV) in myocardial regions of interest can
J. Carberry, D. Carrick, C. Haig, S. Rauhalammi, N. Ahmed, I. Mordi, M. McEntegart, M. Petrie, H. Eteiba, S. Hood, S. Watkins, M. Lindsay, A. Davie, A. Mahrous, I. Ford, N. Sattar, P. Welsh, A. Radjenovic, K. Oldroyd, C. Berry   +19 more
semanticscholar   +1 more source

Systematic Analysis of Gene Expression Differences between Left and Right Atria in Different Mouse Strains and in Human Atrial Tissue

, 2011
Background: Normal development of the atria requires left-right differentiation during embryonic development. Reduced expression of Pitx2c (paired-like homeodomain transcription factor 2, isoform c), a key regulator of left-right asymmetry, has recently ...
Fabritz Larissa, Brown Nigel A., Hoffmeier Andreas, Hans Schöler, Piccini, Ilaria, Brown, NA, Scheld, Hans H, Greber, B, Kahr, Peter C, Piccini Ilaria, Boris Greber, Greber Boris, Schöler, H, Hans H. Scheld, Ilaria Piccini, Nigel A Brown, Kahr Peter C., Kahr, PC, Fabritz, Larissa; id_orcid, Hans H Scheld, Piccini, I, Schöler Hans, Kirchhof Paulus, Peter C. Kahr, Brown, Nigel A, Scheld, HH, Kirchhof, P, Fabritz, L, Kirchhof, Paulus; id_orcid, Paulus Kirchhof, Schöler, Hans, Scheld Hans H., Greber, Boris, Hoffmeier, A, Peter C Kahr, Larissa Fabritz, Nigel A. Brown, Andreas Hoffmeier, Hoffmeier, Andreas   +38 more
core   +1 more source

Oral Bioinspired Peroxisome‐Engineered Probiotics for Modulating Gut Microbiota Homeostasis and Alleviating Cardiac Chemotherapy Toxicity

Advanced Science, EarlyView.
This study developed an oral bioinspired peroxisome‐engineered probiotic (BPEP) by anchoring lipid‐encapsulated ruthenium nanozymes onto Escherichia coli Nissle 1917, utilizing probiotics to deliver nanozymes to the intestinal barrier for reactive oxygen species/reactive nitrogen species elimination, tight junction restoration, and gut microbiota ...
Shuyu Wang, Xiaowan Fan, Chao Zhang, Shuai Han, Yike Guo, Yuchen Wang, Wei Wang, Junyue Xing, Ying Liu, Wei Jiang, Xiaoying Chen   +10 more
wiley   +1 more source

Effects of trimetazidine on ventricular remodeling in coronary artery disease patients with left ventricular hypertrophy: the rationale and design of a randomized controlled trial

BMC Cardiovascular Disorders, 2020
Background Trimetazidine is a metabolic anti-ischemic agent, which increases the tolerance of cardiomyocytes to ischemia. However, few studies have explored the effect of trimetazidine on ventricular remodeling in coronary artery disease (CAD) patients ...
Lili Wu, Yi Luan, Ya Li, Min Wang, Jialin He, Chongying Jin, Wenbin Zhang   +6 more
doaj   +1 more source

The effect of exercise training on transverse tubules in normal, remodeled, and reverse remodeled hearts [PDF]

, 2011
The response of transverse (T)-tubules to exercise training in health and disease remains unclear. Therefore, we studied the effect of exercise training on the density and spacing of left ventricle cardiomyocyte T-tubules in normal and remodeled hearts ...
Kemi, Ole J., Wisloff, Ulrik, Koch, Lauren G., Morten A. Hoydal, MacQuaide, Niall, Haram, Per M., Godfrey L. Smith, Steven L. Britton, Hoydal, Morten A., Smith, Godfrey L., Ellingsen, Oyvind, Per M. Haram, Lauren G. Koch, Oyvind Ellingsen, Britton, Steven L., Niall MacQuaide, Ole J. Kemi, Ulrik Wisloff   +17 more
core   +1 more source

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

Advanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng, Kaiwen Chen, Qiwei Ying, Shuya Wang, Xin Li, Guanlin Li, Yantao Zhao, Binghua Ma, Huanan Wang, Dawei Li, Lijun Zhang, Jian Zhang, Yu Zhao, Changle Ren, Baodong Chen, Yueming Song   +15 more
wiley   +1 more source

Effects of Erythropoietin on Cardiac Remodeling After Myocardial Infarction

Journal of Pharmacological Sciences, 2006
.: Erythropoietin (EPO) has been suggested to have a cardioprotective effect against ischemia. The purpose of this study was to examine the effects of EPO on cardiac remodeling after myocardial infarction (MI).
Nishiya Daisuke, Omura Takashi, Shimada Kenei, Matsumoto Ryo, Kusuyama Takanori, Enomoto Soichiro, Iwao Hiroshi, Takeuchi Kazuhide, Yoshikawa Junichi, Yoshiyama Minoru   +9 more
doaj   +1 more source