Results 171 to 180 of about 547,971 (352)

Animal models of chronic thromboembolic pulmonary hypertension

Animal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu, Lin‐Chao Zhou, Xiao‐Xue Zhang, Xiao‐Yang Ren, Yi Yan, Shao‐Fei Liu   +5 more
wiley   +1 more source

Effect of Exercise Training on Left Ventricular Remodeling in Diabetic Patients with Diastolic Dysfunction: Rationale and Design

, 2014
Introduction This study will examine the effects of combined aerobic and resistance training on left ventricular remodeling in diabetic patients with diastolic dysfunction.
Srivastava, PM, Hare, David L, Steve Selig, Itamar Levinger, Muhammad Asrar ul Haq, Chiew Wong, Ul Haq, MA, Deidre Toia, Levinger, Itamar, Jerums, G, Toia, Deidre, Melissa Sbaraglia, Piyush M. Srivastava, Toia, D, Hare, DL, George Jerums, Levinger, I, Piyush M. Srivastava,, David L. Hare, Wong, C, Sbaraglia, Melissa, Selig, S, Sbaraglia, M   +22 more
core   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Insights into cardiac remodelling by multi-modal magnetic resonance imaging and spectroscopy [PDF]

, 2005
EThOS - Electronic Theses Online ServiceGBUnited ...
PETERSEN, SE, Petersen, Steffen E
core  

0031: Predictive factors of left ventricular remodeling after myocardial infarction. Angiographic and MRI point of view

, 2014
Background/aimseveral months after myocardial infarction, many patients will develop left ventricular remodeling and heart failure. The aim of this study was to bring out predictive factors of left vetricular remodeling especially angiographic and MRI ...
Cescau, Arthur
core   +1 more source

Evaluation of cardiac histology and cell death markers during the progression of diabetes in a streptozotocin‐induced diabetes rat model

Animal Models and Experimental Medicine, EarlyView.
Daily insulin administration in streptozotocin‐induced diabetic rats prevented cardiac damage associated with diabetic cardiomyopathy, including hypertrophy, fibrosis, and expression of cell death markers, at 12 weeks. However, cyclophilin D, a marker of mitochondrial permeability transition pore‐opening‐associated cell death (necrosis), was observed ...
Tamara Sáez, Ivo Carrasco‐Wong, Juan Varas, Sebastián San Martín, Jaime A. Riquelme, Rienzi Díaz‐Navarro   +5 more
wiley   +1 more source

Guideline-Directed Medical Therapy Intensity, Ventricular Remodeling, and Clinical Outcomes After Acute Myocardial Infarction: A Single-Center Real-World Retrospective Cohort Study

Biomedicines
Background: Guideline-directed medical therapy (GDMT) is recommended after acute myocardial infarction (AMI), particularly in patients with left ventricular systolic dysfunction, yet real-world implementation remains suboptimal.
Teodora Mateoc-Sîrb, Ioana-Maria Suciu, Dan Gaiță, Andor Minodora, Roxana Popescu, Tania Vlad, Călin Muntean, Daliborca-Cristina Vlad   +7 more
doaj   +1 more source

Cardiac Device Algorithms for Optimal Outcomes in Patients with Sick Sinus Syndrome [PDF]

, 2013
Sick sinus syndrome (SSS) is a relatively common chronic condition affecting the electrical conduction system of the heart. In the absence of any reversible cause of SSS, the most effective treatment is implantation of a permanent pacemaker to maintain ...
CURRY, JANE,KATHERINE
core  

Chrysin alleviates pressure overload–induced myocardial remodeling through regulating the PI3K/AKT/NRF2 pathway–mediated oxidative stress response

Animal Models and Experimental Medicine, EarlyView.
In this study, we primarily simulated pathological myocardial remodeling induced by transverse aortic constriction surgery and found significant cardiac hypertrophy and fibrosis, characterized by deteriorated cardiac function. Oxidative stress response is considered as a pivotal pathological process, which contributes to inflammation and apoptosis of ...
Yijia Wang, Xing Feng, Shuhui Zhao, Yuchong Fu, Ao Zhang, Xiaofeng Shen, Bowen Yu, Yihao Wang, Jiahui Lin, Bing Zhang, Weiping Ji, Lianpin Wu, Xiaoling Guo   +12 more
wiley   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source