Results 61 to 70 of about 547,971 (352)

Diabetes Mellitus and Heart Failure With Preserved Ejection Fraction: Role of Obesity

Frontiers in Physiology, 2022
Heart failure with preserved ejection fraction is a growing epidemic and accounts for half of all patients with heart failure. Increasing prevalence, morbidity, and clinical inertia have spurred a rethinking of the pathophysiology of heart failure with ...
Aneesh Dhore-patil, Aneesh Dhore-patil, Tariq Thannoun, Tariq Thannoun, Rohan Samson, Rohan Samson, Thierry H. Le Jemtel, Thierry H. Le Jemtel   +7 more
doaj   +1 more source

Surgical Left Ventricular Remodeling in Heart Failure [PDF]

European Journal of Heart Failure, 2005
Abstract The high mortality and morbidity of patients in terminal heart failure are a therapeutic challenge to modern medicine. Surgically, cardiac transplantation is an excellent treatment for many patients. However, lack of donors combined with an increasing number of patients has led to the search for other surgical strategies ...
Theis, Tønnessen, Cathrine Wold, Knudsen   +1 more
openaire   +2 more sources

The role of urate and xanthine oxidase in vascular oxidative stress:Future directions [PDF]

, 2009
Vascular oxidative stress has been shown to be a potent factor in the pathophysiology of endothelial dysfunction. Despite current optimal evidence-based therapy, mortality from various cardiovascular disorders remains high.
Allan Struthers, Jacob George, George, Jacob, Struthers, Allan   +3 more
core   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source

Athlete’s Heart in Elite Biathlon, Nordic Cross—Country and Ski-Mountaineering Athletes: Cardiac Adaptions Determined Using Echocardiographic Data

Journal of Cardiovascular Development and Disease, 2021
Twelve world elite Biathlon (Bia), ten Nordic Cross Country (NCC) and ten ski-mountaineering (Ski-Mo) athletes were evaluated for pronounced echocardiographic physiological cardiac remodeling as a primary aim of our descriptive preliminary report.
Paul Zimmermann, Othmar Moser, Max L. Eckstein, Jan Wüstenfeld, Volker Schöffl, Lukas Zimmermann, Martin Braun, Isabelle Schöffl   +7 more
doaj   +1 more source

Biomarkers of Left Ventricular Hypertrophy and Remodeling in Blacks [PDF]

Hypertension, 2011
Left ventricular (LV) hypertrophy, a marker for adverse cardiovascular events, is more common in blacks than in non-Hispanic whites. Mechanisms leading to LV hypertrophy and mediating its clinical sequelae in blacks are not fully understood. We investigated the associations of 39 candidate biomarkers in distinct biological pathways with LV
Thais, Coutinho, Malik, Al-Omari, Thomas H, Mosley, Iftikhar J, Kullo   +3 more
openaire   +2 more sources

miR-199b-5p is a regulator of left ventricular remodeling following myocardial infarction

Non-coding RNA Research, 2017
Myocardial infarction (MI), the globally leading cause of heart failure, morbidity and mortality, involves post-MI ventricular remodeling, a complex process including acute injury healing, scar formation and global changes in the surviving myocardium ...
B. Duygu, Ella M Poels, R. Juni, N. Bitsch, L. Ottaviani, S. Olieslagers, L. D. de Windt, P. A. da Costa Martins   +7 more
semanticscholar   +1 more source

The effects of a supervised cardiac rehabilitation exercise programme on left ventricular function in patients with ischaemic heart disease (interim report) [PDF]

, 2006
Purpose. This study sought to determine the effects of a supervised cardiac rehabilitation exercise programme on left ventricular function in patients with ischaemic heart disease and any degree of left ventricular systolic dysfunction. Subjects.
Smith, Geoffrey T.
core  

The multi-modality cardiac imaging approach to the Athlete's heart: an expert consensus of the European Association of Cardiovascular Imaging [PDF]

, 2015
peer reviewedThe term 'athlete's heart' refers to a clinical picture characterized by a slow heart rate and enlargement of the heart. A multi-modality imaging approach to the athlete's heart aims to differentiate physiological changes due to intensive ...
Galderisi, Maurizio, Popescu, Bogdan A., Cosyns, B, Petersen, SE, Cardim, Nuno, DAVIN, Laurent, Schroeder, S, Kitsiou, Anastasia, Cosyns, Bernard, Lancellotti, Patrizio, Petersen, Steffen E., Habib, G, Kitsiou, A, Edvardsen, T, Davin, L, Cardim, N, Bruder, Oliver, Popescu, Bogdan Alexandru, Burgstahler, C, D'Andrea, Antonello, Donal, E, Bruder, O, Plein, S, Freitas, A, Freitas, Antonio, Burgstahler, Christof, Galderisi, M, Edvardsen, Thor, Donal, Erwan, Lancellotti, P, Plein, Sven, D'Andrea, A, Schroeder, Stephen, Habib, Gilbert, Popescu, BA   +34 more
core   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source