Results 71 to 80 of about 547,971 (352)

Differentiation of left ventricular deformation using 2D speckle tracking based on left ventricular geometric pattern in a hypertensive population: a single-center study

Arterial Hypertension
BACKGROUND: Left ventricular (LV) adaptation to arterial hypertension can result in different geometric responses with different hemodynamic patterns.
Mefri Yanni, Nani Nani, Wulan Prisilla
doaj   +1 more source

The effect of rosuvastatin on inflammation, matrix turnover and left ventricular remodeling in dilated cardiomyopathy: a randomized, controlled trial.

PLoS ONE, 2014
BackgroundDilated cardiomyopathy is characterized by left ventricular dilatation and dysfunction. Inflammation and adverse remodeling of the extracellular matrix may be involved in the pathogenesis.
Kaspar Broch, Erik T Askevold, Erik Gjertsen, Thor Ueland, Arne Yndestad, Kristin Godang, Wenche Stueflotten, Johanna Andreassen, Rolf Svendsmark, Hans-Jørgen Smith, Svend Aakhus, Pål Aukrust, Lars Gullestad   +12 more
doaj   +1 more source

Left Ventricular Post-Infarct Remodeling: Implications for Systolic Function Improvement and Outcomes in the Modern Era.

JACC. Heart failure, 2019
OBJECTIVES This study sought to investigate the impact of post-infarct left ventricular (LV) remodeling on outcomes in the contemporary era. BACKGROUND LV remodeling after ST-segment elevation myocardial infarction (STEMI) is associated with heart ...
P. van der Bijl, R. Abou, L. Goedemans, B. Gersh, D. Holmes, N. Ajmone Marsan, V. Delgado, Jeroen J. Bax   +7 more
semanticscholar   +1 more source

Effects of steady state free precession parameters on cardiac mass, function, and volumes. [PDF]

, 2007
PURPOSE: We aimed to investigate comparability of LV volumes, function, and mass acquired with three steady-state free precession (SSFP) pulse sequences, simulating typical vendor and protocol specific differences in data acquisition. METHODS: Twenty-one
Francis, JM, Hudsmith, LE, Robson, Matthew, Neubauer, S, Petersen, SE, Robson, MD, Neubauer, Stefan, Hogan, MC   +7 more
core   +1 more source

Microfabricated Anisotropic Myobundles for the Scalable Production of Cardiac Tissue Grafts

Advanced Functional Materials, EarlyView.
Controlling the anisotropy of cardiac tissue remains an outstanding challenge in the field of cardiac tissue engineering. Here, we introduce an approach to generate anisotropic cardiac myobundles using cell‐adhesive, synthetic, electrospun fibers and stem cell‐derived cardiac fibroblasts.
Maggie E. Jewett, Javiera Jilberto, Margaret E. Stanley, David O. Ntim, Siddhi M. Bhirud, Avianna T. Schroeder, Gonzola X. Anyosa Galvez, Jingyi Xia, Samuel J. DePalma, Emmanouil Agrafiotis, Susan S. Xi, Amanda S. Bluem, Courtney M. Lestock, Adam S. Helms, David A. Nordsletten, Brendon M. Baker   +15 more
wiley   +1 more source

Altitude‐Related Differences in Biventricular Remodeling and the Clinical Profile of Pulmonary Hypertension: An Exploratory Cardiovascular Magnetic Resonance Study

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Residence at high altitudes (HAs) may increase cardiovascular risk due to hypobaric hypoxia, but its synergy with pulmonary hypertension cause is unclear.
Wanlin Peng, Wei Bai, Xinyang Lyu, Xu Xu, Keling Liu, Sixian Hu, Wen Zeng, Ting Luo, Yi Luo, Yunlong Hu, Chuan Tian, Xiaoyue Zhou, Zhenlin Li, Chunchao Xia   +13 more
doaj   +1 more source

Short term Pm2.5 exposure caused a robust lung inflammation, vascular remodeling, and exacerbated transition from left ventricular failure to right ventricular hypertrophy

Redox Biology, 2019
Heart failure (HF) is the single largest cause for increased hospitalization after fine particulate matter (PM2.5) exposure. Patients with left HF often progress to right ventricular (RV) failure even with optimal medical care. An increase of PM2.5 of 10 
W. Yue, Lei Tong, Xiaohong Liu, X. Weng, Xiaoyu Chen, Dongzhi Wang, Samuel C. Dudley, E. K. Weir, Wenjun Ding, Zhongbing Lu, Yawei Xu, Yingjie Chen   +11 more
semanticscholar   +1 more source

Subcellular heterogeneity of ryanodine receptor properties in ventricular myocytes with low T-tubule density [PDF]

, 2011
Rationale: In ventricular myocytes of large mammals, not all ryanodine receptor (RyR) clusters are associated with T-tubules (TTs); this fraction increases with cellular remodeling after myocardial infarction (MI).
MacQuaide, N., Bito, Virginie, Smith, G.L., Macquaide, Niall, Biesmans, L., Godfrey L. Smith, Frank R Heinzel, Sipido, Karin R., Karin R Sipido, Smith, Godfrey L., Rota, M., Heinzel, F.R., Godfrey L Smith, Bito, V., Sipido, K.R., Heinzel, Frank R., Niall Macquaide, Liesbeth Biesmans, Biesmans, Liesbeth, Virginie Bito, Frank R. Heinzel, Karin R. Sipido   +21 more
core   +1 more source

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

Advanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin, Alexander Chen, Quincy P. Lyons, Michael B. Nguyen, Maria L. Karkanitsa, Justin Yu, Van K. Ninh, Emily Gardner, Elyse G. Wong, Sriya N. Paleti, Julian Cheng, Benjamin D. Bridgelal, Kate E. Reimold, Selena Cao, Connor Uhre, Colin G. Luo, Zhenxing Fu, Kevin R. King, Karen L. Christman   +18 more
wiley   +1 more source

Therapeutic Stalemate in Heart Failure With Preserved Ejection Fraction

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
The findings of randomized trials of neurohormonal modulation have been neutral in heart failure with preserved ejection fraction and consistently positive in heart failure with reduced ejection.
Rohan Samson, Thierry H. Le Jemtel
doaj   +1 more source