Results 41 to 50 of about 373,573 (310)

Legal Linguistics of Judicial Educational Activities

open access: yesBulletin of Kharkiv National University of Internal Affairs, 2019
The objective of the study is to provide characteristics to the state of academic discipline “Legal Linguistics” in Ukraine and in the countries of Romano-Germanic law, and its origin.
О. V. Minchenko
doaj   +1 more source

Legal Regulation of Standardization and Certification of Space Objects [PDF]

open access: yesAdvanced Space Law, 2019
The article provides a comparative analysis of international law and national legislation of Ukraine on the legal regulation of space activities. Such institutions of state regulation of objects of space activities as registration and certification are ...
Olha Yeshchuk, Mariia Novikova
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Issues of the legal status of municipal public chambers: a view from Russia

open access: yesRevista Brasileira de Direito, 2023
The paper analyzes the main theoretical and practical legal issues related to the legal status and activities of municipal public chambers in modern Russia.
Sergey Solovev   +2 more
doaj   +1 more source

The distribution of legal traditions around the world : A contribution to the legal-origins theory

open access: yes, 2014
The distribution of the common law was conditioned by a colonial strategy sensitive to the colonies’ level of endowments, exhibiting a more effective implantation of the legal system in initially sparsely populated territories with a temperate climate ...
Oto-Peralías, Daniel   +1 more
core   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

The use of reference legal systems in the educational activity of lawyers

open access: yesВестник Майкопского государственного технологического университета, 2023
The relevance of the research topic is characterized by a high level of informatization in the professional activities of lawyers and the need to develop practical skills in using reference legal systems of students in the educational process.The ...
Natalya Mikhailovna Suetina
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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