Results 71 to 80 of about 442,857 (309)

TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

open access: yesAdvanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi   +8 more
wiley   +1 more source

Legislation

open access: yes, 1971
Print began with 1971.This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Mode of access: Internet from the ...

core  

Bench‐to‐Bedside Translation of Self‐Healing Colloidal Hydrogels as Next Generation Design of Flowable Hemostatic Matrix: From Preclinical Evaluation to Human Clinical Trials

open access: yesAdvanced Science, EarlyView.
ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng   +15 more
wiley   +1 more source

Thriving in the Legal Academy

open access: yes, 2007
Arts, Education & Law Group, School of LawNo Full ...
Baron, Paula
core  

Clinical legal education across the globe

open access: yes
This chapter reviews the development of clinical legal education in different parts of the world and provides an account of clinical legal scholarship, drawing on a wide range of sources.
Giddings, J
core   +1 more source

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

The concept of professional judicial representation and the problem of modern legal education quality

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2019
The problem of introducing the institute of professional judicial representation in line with special qualification requirements into commercial, civil, and administrative procedures has been considered. Based on the analysis of the legislation concerned
I.M. Divin
doaj   +1 more source

Embracing and Making Change in Legal Education: Serving the Law Students of Today and Tomorrow

open access: yes, 2021
Danielle M. Conway is Dean and Donald J. Farage Professor of Law at Penn State Dickinson Law. The following are her keynote remarks delivered Jan. 6, 2021, for the 2021 AALS Joint Section Program of the Sections on Student Services and Part-Time Division,
Conway, Danielle M.
core  

Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education

open access: yesAdvanced Science, EarlyView.
We investigate whether Montessori and traditional schooling systems shape the developmental trajectory of large‐scale brain dynamics in different ways. We quantify the arrow of time (“non‐reversibility”) in neural activity during resting state and movie‐watching, revealing distinct maturational patterns.
Elvira del Agua   +6 more
wiley   +1 more source

Kilka słów o klinikach prawa

open access: yesFilozofia Publiczna i Edukacja Demokratyczna, 2013
Clinical teaching reflects the need to combine theory in the teaching of the law and practical skills. It creates the possibility of „being a lawyer” still at the stage of university education.
Magdalena Klauze
doaj   +1 more source

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