Results 81 to 90 of about 442,857 (309)

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

A Piezo‐Mimetic Ionic Hydrogel Harnessing Joint Motion for Cartilage Repair

open access: yesAdvanced Science, EarlyView.
A piezo‐mimetic ionic hydrogel converts mechanical deformation into bioactive ionic currents via stress‐induced asymmetric ion migration. Coupled with sustained Mg2+ release, this mechano‐electrochemical platform bridges mechanical loading and cellular signaling, enabling load‐adaptive stimulation and enhanced cartilage regeneration. ABSTRACT Articular
Chenyuan Gao   +14 more
wiley   +1 more source

PEDAGOGICAL ASPECTS OF IMPROVING THE LEGAL EDUCATION OF THE FUTURE OFFICERS OF MIA RUSSIA

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
The purpose of this article is to examine the nature and structure of pedagogical support of improving the legal education of future officers. The methodological basis of the work performed research work on the provisions of the methodology and methods ...
Alexey Nikolaevich Kononov
doaj   +1 more source

A Rationale and Framework for Digital Literacies in Legal Education

open access: yes, 2017
Assessments of the fitness for purpose of legal education are many and varied. Both broad and specific reviews have been frequently undertaken in the context of higher education, admission requirements and professional standards, and national ...
Galloway, Kathrine
core  

Global Clinical Legal Education

open access: yes
This book explores the distinctive nature of clinical legal education in a range of global contexts. The emergence of law school-based clinical legal education has been recognised as a major innovation in modern legal education.
-
core   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

open access: yesAdvanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin   +11 more
wiley   +1 more source

THE IMPORTANCE OF LEGAL AWARENESS AND LEGAL CULTURE IN LEGAL EDUCATION AND EDUCATION

open access: yes
This article analyzes the importance of legal upbringing and education in the development of legal consciousness and legal culture in society. Also, some solutions to this issue are given.
openaire   +2 more sources

Widening participation in higher education: The legacy for legal education [PDF]

open access: yes, 2013
New Labour’s first administration pledge to enable 50% of the adult population to pass through higher education by 2010 was predicated on the notion that an educated nation is beneficial and as such is linked to its long-term economic well-being.
Waters, B.
core   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy