Results 41 to 50 of about 16,631 (259)

Ontology of secrecy in the legal paradigm: comparative legal analysis

open access: yesЮридический вестник Самарского университета
The study is devoted to the theoretical and legal analysis of the phenomenon of secrecy as a complex interdisciplinary category. The work reveals the legal nature of secrecy through the prism of its dualistic essence: as an object of legal protection and
A. V. Sidorova
doaj   +1 more source

PDHA1 Hyperactivation‐Mediated Glucose Metabolism Reprogramming Fuels Neutrophil NETosis and Promotes Acute Lung Injury

open access: yesAdvanced Science, EarlyView.
During NETosis, neutrophils shift metabolically toward enhanced OXPHOS and partially reduced glycolysis. This shift is driven by PDHA1 hyperactivity‐dependent selective metabolic reprogramming. The neutrophil‐targeted nanoparticle 3‑FP‑BSA NPs effectively inhibit NETosis and attenuate ALI.
Yu‐Biao Liu   +14 more
wiley   +1 more source

Ontologia społeczna w świetle filozofii Romana Ingardena

open access: yesAnaliza i Egzystencja, 2023
In social ontology are conducts investigations into how social and institutional facts exist, what is a social group or collective intentionality. Phenomenology is one of the 20th-century philosophical movements whose contributions of its representatives
Artur Kosecki
doaj   +1 more source

Symptom‐Driven Prediction of Chronic Multimorbidity with a Macro–Micro Heterogeneous Graph Neural Network

open access: yesAdvanced Science, EarlyView.
Clinical symptoms offer a window into multimorbidity. A macro‐micro heterogeneous graph neural network integrates clinical records with biomedical knowledge to improve patient‐level symptom‐disease association learning and visit‐level multimorbidity completion.
Yiheng Ye   +15 more
wiley   +1 more source

Ontology-Driven Legal Rule Auditor for Secure, Trustworthy, and Governed RAG Systems

open access: yesComputers
Large Language Models (LLMs) have significant potential in regulated domains such as law, healthcare, and compliance, where users need help interpreting complex rules and documents.
Aymen Akremi
doaj   +1 more source

Ontological approach to knowledge of the legal psychology value system

open access: yesПсихология и право, 2020
The article reflects the individual results of the process of knowledge of the value system of legal psychology. The value system of legal psychology is considered as a set of interconnected ideals and meanings developed on the basis of the integration ...
Ilyina V.A.
doaj   +1 more source

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

open access: yesAdvanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou   +21 more
wiley   +1 more source

Lex biomedica: concept, nature and ontology

open access: yesАкушерство, гинекология и репродукция, 2020
The article is devoted to the study and explanation of the meaning, nature, structure, features and ontology of extra-legal regulation in the field of healthcare and medicine (lex biomedica). The authors explain the concept and structure of lex biomedica.
I. V. Ponkin, A. A. Ponkina
doaj   +1 more source

Early‐Life Polyethylene Microplastic Exposure Exacerbates ADHD‐Like Behaviors in Mice via PI3K/AKT1/Nrf2 Signaling: Evidence From the Pilot Cohort and Multi‐Omics Analyses

open access: yesAdvanced Science, EarlyView.
Circulating polyethylene microplastic burden is positively associated with heightened ADHD symptom severity and systemic redox‐inflammatory imbalance in children. Mechanistic investigation in a developmental co‐exposure mouse model further demonstrates that microplastics aggravate ADHD‐like behaviors, dopaminergic dysregulation, and oxidative ...
Yufan Luo   +12 more
wiley   +1 more source

Legal Ontology, Scientific Expertise and The Factual World

open access: yesJournal of Social Ontology, 2016
This article analyses the role of scientific information in legal proceedings by exploring the relationship of law, science and the factual world. The article compares legal and scientific ontology, and discusses how they relate to each other.
Lena Wahlberg
doaj  

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