Results 41 to 50 of about 3,209,823 (291)

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Uma ontologia para representação do conhecimento jurídico-penal no contexto dos delitos informáticos [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Gestão do ConhecimentoO objetivo primordial desta dissertação é propor uma ontologia para representar o conhecimento jurídico-penal sobre ...
Ramos Júnior, Hélio Santiago
core  

General-Process-Ontology/ontology: v0.2.0

, 2023
Full Changelog: https://github.com/General-Process-Ontology/ontology/commits/v0.2.
Simon Stier
core   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Legal Ontology, Scientific Expertise and The Factual World

Journal of Social Ontology, 2016
This article analyses the role of scientific information in legal proceedings by exploring the relationship of law, science and the factual world. The article compares legal and scientific ontology, and discusses how they relate to each other.
Lena Wahlberg
doaj  

Ontology of secrecy in the legal paradigm: comparative legal analysis

Юридический вестник Самарского университета
The study is devoted to the theoretical and legal analysis of the phenomenon of secrecy as a complex interdisciplinary category. The work reveals the legal nature of secrecy through the prism of its dualistic essence: as an object of legal protection and
A. V. Sidorova
doaj   +1 more source

Ontologies in the Legal Domain

, 2010
‘Legal ontology’ is the common denominator for a varying set of models focusing on legal domains, their ‘environments’, legal argumentation and other legal and legally relevant phenomena. Their nature and classification are explained in this article.
openaire   +2 more sources

Ontology-based domain modelling for consistent content change management [PDF]

, 2010
Ontology-based modelling of multi-formatted software application content is a challenging area in content management. When the number of software content unit is huge and in continuous process of change, content change management is important.
Abgaz, Yalemisew, Abgaz, Yalemisew Mintsnote, Pahl, Claus, Javed, Muhammad   +3 more
core   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Ontology Knowledge Map Approach Towards Building Linked Data for Vietnamese Legal Applications

Vietnam Journal of Computer Science
Today, every aspect of society’s activities is regulated by laws from the national and local levels. The increasing number of legal documents interwoven with each other also leads to difficulties in searching and applying in practice.
Hung Q. Ngo, Hien D. Nguyen, Nhien-An Le-Khac   +2 more
doaj   +1 more source