Results 41 to 50 of about 90,256 (303)
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Legal Positivism Influence on Law Enforcement and Judicial Practice in Indonesia
JustisiThe study aims to examine the influence of legal positivism on law enforcement and judicial practices in Indonesia, particularly in the context of its limitations in realizing substantive justice. The main focus is on the issues of customary land rights,
Renita Kamil
doaj +1 more source
Journal of Law and Legal Reform, 2021 Law is a rule or means in the administration of the state, in order to achieve an orderly, safe and secure life, the rights of the community are required. According to positivism, law is an order from those who hold the highest power or hold sovereignty.
Kartika Nur Cahyani
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Ontology and Reason Giving in Law [PDF]
, 2016 John Gardner has noted that legal positivism is more a theory of legal validity than it is a theory about law ’ s nature. 1 This is true in that one can be a legal positivist and hold a variety of different theories about law ’ s nature, but not to the
Ehrenberg, Kenneth M.
core +1 more source
Kelsen's Legal Positivism and the Challenge of Nazi Law [PDF]
, 2014 Kelsen’s legal positivism has often been criticized for having supported the compliance of the\ud German judiciary with Nazi law. Especially Kelsen’s insistence on the separation of law and\ud morality was considered as a crucial deficiency.
Pauer-Studer, Herlinde
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
The Influence of Positivism and Empirism in The Enforcement of Islamic Inheritance Law in Indonesia
Substantive Justice International Journal of LawPositivism and empiricism are modern paradigms become the basic guidelines for the schools of legal philosophy, namely legal positivism and legal realism.
Jamrud Qomaruz Zaman +4 more
doaj +1 more source
Refleksi Paradigma Ilmu Pengetahuan Bagi Pembangunan Hukum Pengadaan Tanah
Bestuur, 2020 The purpose of this study is to explain the influence of the positivism paradigm in making land acquisition law and its application which is oriented towards formalism in Indonesia.
Lego Karjoko +2 more
doaj +1 more source
Kritik terhadap Paradigma Positivisme Hukum dan Beberapa Pemikiran dalam Rangka Membangun Paradigma Hukum yang Berkeadilan [PDF]
, 2014 Science of law is something that is constantly changing, moving and flowing. If the base of departure is the assumption of legal positivism and legal positivism paradigm basic criteria that need to be tested, whether in the present development is still ...
Maryati, M. (Maryati)
core