Results 61 to 70 of about 90,256 (303)

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Implikasi Aliran Positivisme terhadap Pemikiran Hukum [PDF]

open access: yes, 2010
Law positivism strictly separates the existing law and the law wich should have properly been existing, isolates law from its non-legal elements, and puts it in front ot he written law or regulations as a command from legal authority.
Najwan, J. (Johni)
core  

Legal Positivism

open access: yes, 2021
This paper presents different stands on legal positivism, as philosophical positivism is similar to it and is an idea without which we cannot understand or explain the epistemological foundations of the knowledge of positive law. This thought, common to the social sciences that embrace the philosophical and scientific postulates of positivism, involves
Carrillo de la Rosa, Yezid   +1 more
openaire   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Moral Cognitivism and Legal Positivism in Habermas’s and Kant's Philosophy of Law

open access: yesEthic@: an International Journal for Moral Philosophy, 2017
The hypothesis of this paper is that legal positivism depends on the non plausibility of strong moral cognitivism because of the non necessary connection thesis between law and morality that legal positivism is supposed to acknowledge.
Delamar José Volpato Dutra   +1 more
doaj   +1 more source

Legal Positivism: The Leading Legal Theory in America [PDF]

open access: yes, 2005
The author discusses the transition in from a Natural Law base for American Jurisprudence to legal ...
Rickert, Paul R
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall   +16 more
wiley   +1 more source

INFLUENCE OF OF LEGAL POSITIVISM ON FORMING PHILOSOPHICAL AND LEGAL IDEAS IN DECISION MAKING BY THE SUPREME COURT OF THE USA

open access: yesВісник НЮУ імені Ярослава Мудрого: Серія: Філософія, філософія права, політологія, соціологія, 2019
Problem setting. In the period of the establishment of statehood and to correct mistakes that have already occurred, there is an urgent need to understand such a theoretical heritage and practical experience.
Ганна Вікторівна Коваленко
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

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