Results 31 to 40 of about 977,277 (349)

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

SELF-MURDER AND SELF-MURDERERS IN SOCIAL REPRESENTATIONS OF YOUNG RUSSIANS: AN EXPLORATORY STUDY

Psichologija, 2015
Premature death caused by self-murder is one of the most serious problems of public health in the world. About one million people disappear for this reason each year, and the further estimations are quite pessimistic. There are no doubts that the current
Nikolay Dvoryanchikov, Inna Bovina, Olesya Vikhristuck, Elizaveta Berezina, Gennady Bannikov, Inga Konopleva   +5 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The Use of Assessment Center Technology for the Prevention and Reduction of Professional Burnout [PDF]

Психологическая наука и образование (2007. Online), 2014
Dynamism of professional activity, increasing workload and working time shortage, high social responsibility for results and other factors increase the probability of formation of burnout in government employees.
Stalnova I.A., , Stalnov A.G
doaj  

Four Decades of the Journal \u3ci\u3eLaw and Human Behavior\u3c/i\u3e: A Content Analysis [PDF]

, 2018
Although still relatively young, the journal Law and Human Behavior (LHB) has amassed a publication history of more than 1300 full-length articles over four decades. Yet, no systematic analysis of the journal has been done until now. The current research
Brank, Eve M., Haby, Joshua A., Hazen, Katherine P., Hoetger, Lori A., Wylie, Lindsey E.   +4 more
core   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

The promise and perils of positive psychology in legal education [PDF]

, 2016
This paper introduces positive psychology in general and Positive Psychology in particular, and argues that legal education may benefit from utilisation of positive psychology.
Ferris, G
core  

Soft Robotic Excretory Care Simulator for Nursing Education: Functional and Perceptual Biomimetics Approach

Advanced Robotics Research, EarlyView.
A soft robotic simulator is developed to replicate the digital removal of feces (DRF), a sensitive yet essential nursing procedure. Integrating soft actuators, sensors, and a realistic rectal model, the simulator balances functional fidelity with perceptual realism. Engineering evaluations and nurse feedback confirm its potential to enhance training in
Shoko Miyagawa, Sota Suzuki, Shizuka Watanabe, Zebing Mao, Young Ah Seong, Toshinori Fujie, Tatsuhiro Horii, Kenjiro Tadakuma, Koichi Suzumori, Hiroyuki Nabae, Shingo Maeda   +10 more
wiley   +1 more source

An experimental guide to vehicles in the park

Judgment and Decision Making, 2020
Prescriptive rules guide human behavior across various domains of community life, including law, morality, and etiquette. What, specifically, are rules in the eyes of their subjects, i.e., those who are expected to abide by them?
Noel Struchiner, Ivar R. Hannikainen, Guilherme da F. C. F. de Almeida   +2 more
doaj   +1 more source