Results 101 to 110 of about 3,059,732 (298)

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Legal Protection In The Sale And Purchase Of Online Game Accounts Prohibited By Developers: A Normatif Study Of Mobile Legends.

Jurnal Hukum Volkgeist
The development of digital technology has spurred the emergence of the practice of buying and selling online game accounts, including in the game Mobile Legends.
Muchammad Ariqul Baihaqi, Lintang Yudhantaka   +1 more
doaj   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

Promoting Equal Protection and Regulatory Remedies for Balanced Civic Education

Laws
This article examines the teaching of civic engagement in academic settings, focusing on its role in generating new knowledge and fostering social and personal action.
Peder Humlen
doaj   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Legal Remedies for Spoiled Vacations

, 2006
The word "vacation" means to empty oneself of work and other toils, replacing them with leisure and refreshment. When these vacations go bad, consumers have a compound loss -- the unrecoverable waste of the annual pleasure period, the exasperation of longlaid plans gone awry, the helplessness that accompanies captivity away from home, and the financial
openaire   +2 more sources

Ohio DDP and funding for individual options waiver

, 2006
Title from PDF cover (viewed on Jan. 22, 2007).; "September 2006"--P. 3 of cover.; Harvested from the web on 1/22/07Frequently asked questions about the Individual Options Waiver of the Ohio Developmental Disabilities Profile (ODDP) answered by the Ohio ...
Ohio Legal Rights Service.
core  

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Transcription Factor HOXC11 Drives Colorectal Cancer Progression and Metastasis via CAMK2A‐Dependent CXCL5 Upregulation

Advanced Science, EarlyView.
HOXC11 drives colorectal cancer progression by transcriptionally activating CAMK2A, which triggers NF‐κB–dependent CXCL5 upregulation. CXCL5–CXCR2 signaling further reinforces HOXC11 expression through the ERK1/2–SP1 axis, forming a prometastatic positive feedback loop that is effectively disrupted by combined CAMK2A and CXCR2 inhibition.
Qingyang Sun, Hengjie Xu, Sheng Yang, Jiahui Zhou, Chuanxin Tian, Hongxu Nie, Chi Jin, Tuo Wang, Zhihao Chen, Junwei Tang, Yifei Feng, Xiaowei Wang, Yueming Sun   +12 more
wiley   +1 more source

PEMBERIAN GANTI RUGI BERUPA KOMPENSASI TERHADAP KORBAN TINDAK PIDANA (Kajian Yuridis Putusan Pengadilan Negeri Kediri Nomor 30/Pid.B/2022/PN.Kdr, j.o, Putusan Pengadilan Tinggi Surabaya Nomor 620/PID/2023/PT.SBY)

Klausula
Scams disguised as online investment schemes, trading robots, and stock investments are currently rampant in the vicinity of our residential areas.
Bagus Wibowo
doaj   +1 more source