Results 61 to 70 of about 1,877,489 (309)

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Optimism and lender liability in the consumer credit market [PDF]

, 2008
Credit purchases of consumer goods are commonly made upon terms governed by an agreement between the lender and the seller. This type of purchase is generally subject to a legal principle of joint responsibility under which the lender and the seller are ...
Iossa, E, Palumbo, G
core  

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Asking (Different) Responsibility Questions: Responsibility and Non-Resposibility in Criminal Law

Bergen Journal of Criminal Law and Criminal Justice, 2016
Legal scholarly analysis of criminal responsibility is typically assumed to encompass non-responsibility. This reflects the influence of the legal-philosophical tradition on the study of criminal responsibility, in which responsibility and non ...
Arlie Loughnan
doaj   +1 more source

Establishing an independent legal aid authority in Hong Kong : lessons from overseas jurisdictions [PDF]

, 2013
This report is an interview based comparative study of the independence (institutional, operational and financial) of Legal Aid Authorities (LAA) in a range of advanced jurisdictions.
Paterson, Alan
core   +1 more source

Validation of the Pediatric Arthritis Ultrasound Scoring System for the Elbow, Wrist, and Finger Joints in Children With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective We aimed to validate the Pediatric Arthritis Ultrasound Scoring System (PAUSS) for upper extremity joints in children with juvenile idiopathic arthritis (JIA). Methods Children with JIA were evaluated for elbow, wrist, or finger arthritis by clinical examination (CE) and musculoskeletal ultrasound (MSUS) with images scored according to the ...
Patricia Vega‐Fernandez, Pinar Ozge Avar‐Aydin, Kelly Rogers, Daniel J. Lovell, Jennifer Huggins, Alexei Grom, Hermine I. Brunner, Grant S. Schulert, Sheila T. Angeles‐Han, Mekibib Altaye, Amy Cassedy, Arthur B. Meyers, Tracy V. Ting   +12 more
wiley   +1 more source

Present Situation of Commitment to Internal and External Social Responsibility of Companies and its Impact on Organizational Performance: A Field Study in the Telecommunication Companies – Yemen

مجلة الدراسات الاجتماعية, 2018
The study aimed to explore the present situation of the commitment to internal and external social responsibility of companies and its impact on organizational performance at the telecommunication companies in the Republic of Yemen.
نوري عبـدالودود الجناعـي, عبدالله جابـر حسـن أبوهـادي   +1 more
doaj   +3 more sources

Corporate Social Responsibility in Supply Chains of Global Brands: A Boundaryless Responsibility? Clarifications, exceptions and implications [PDF]

, 2008
Corporate social responsibility (CSR) is increasingly becoming a popular business concept in developed economies. As typical of other business concepts, it is on its way to globalization through practices and structures of the globalized capitalist world
Amaeshi, Kenneth, Nnodim, Paul, Osuji, Onyeka Kingsley   +2 more
core   +2 more sources

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

THE DEVELOPMENT OF LEGAL RESPONSIBILITY FOR A SOCIALLY RESPONSIBLE BEHAVIOR FOR BUSINESS OPERATORS IN ROMANIA, MEMBER STATE OF EUROPEAN UNION [PDF]

CES Working Papers, 2016
Legal responsibility represents an important component of social responsibility, together with ethical responsibility, ecological responsibility, economical responsibility and philanthropic responsibility.
Laura MURESAN
doaj