Results 81 to 90 of about 2,722,590 (300)

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

Challenges of access to medicine and the responsibility of pharmaceutical companies: a legal perspective

open access: yesDARU Journal of Pharmaceutical Sciences, 2016
The right to health as a basic human right- and access to medicine as a part of it- have been a matter of attention for several decades. Also the responsibilities of different parties- particularly pharmaceutical companies- in realization of this right ...
S. Ahmadiani, S. Nikfar
semanticscholar   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

Responsibility for the legal costs in case of procedural complicity in civil and commercial proceedings

open access: yesПравоприменение, 2019
The subject of the paper are basic principles for the responsibility for the legal costs in case of procedural complicity and consolidation of these principles in the procedural legislation.The purpose of the article is to confirm or disprove hypothesis ...
Julia V. Kaizer
doaj   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang   +10 more
wiley   +1 more source

Present Situation of Commitment to Internal and External Social Responsibility of Companies and its Impact on Organizational Performance: A Field Study in the Telecommunication Companies – Yemen

open access: yesمجلة الدراسات الاجتماعية, 2018
The study aimed to explore the present situation of the commitment to internal and external social responsibility of companies and its impact on organizational performance at the telecommunication companies in the Republic of Yemen.
نوري عبـدالودود الجناعـي   +1 more
doaj   +3 more sources

Legal Responsibility in Environmental Law

open access: yesJournal of Danubian Studies and Research, 2018
The paper aims to make an endeavor in the field of environmental law. It is recognized that the most important role in the field of environmental protection and nature conservation is played by the preventive means of civil or administrative nature ...
Niculescu Iuliana
doaj  

Principle of Responsibility of the Controlling Person as Approach to Eliminating the “Responsibility Gap” for Harm Caused by AI Systems and AI Applications

open access: yesМосковский журнал международного права
INTRODUCTION. The use of artificial intelligence technologies (hereinafter referred to as “AI”) is characterized by the mediation of human actions by autonomous processes, which leads, in the case when technical expertise is unable to identify the causer
E. N. Melnikova
doaj   +1 more source

ADMINISTRATIVE RESPONSIBILITY (THE CONSTITUTIONAL DESIGN)

open access: yesГуманитарные и юридические исследования, 2021
The article studies basic elements of the constitutional design of the administrative responsibility: proportionality of the restriction of citizens' rights and freedoms to the constitutionally signiicant interests and goals; presence of guilt as an ...
I. V. Maximov
doaj  

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