Results 61 to 70 of about 247,591 (259)

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen   +13 more
wiley   +1 more source

REFORMULASI PENGATURAN MENGENAI FINANCIAL TECHNOLOGY DALAM HUKUM POSITIF DI INDONESIA

open access: yesArena Hukum, 2020
  ABSTRACT Financial Technology, one of the disruptive innovations that restructures aspects of the financial industry and influences people's lifestyles, needs to be balanced with the fulfillment of accommodative legal development.
Nurul Ula Ulya, Fazal Akmal Musyarri
doaj   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

open access: yesAdvanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing   +10 more
wiley   +1 more source

Designing technology for legal work

open access: yesOñati Socio-Legal Series
This article discusses how legal professionals perceive the change in their work practices and work-related boundaries as they participate in the design and implementation of a new information system.
Terhi Esko
doaj   +1 more source

Wavelength‐Dependent Photobiomodulation Regulates Macrophage Polarization via Mitochondrial Dynamics and Metabolic Reprogramming

open access: yesAdvanced Science, EarlyView.
Light wavelength encodes distinct macrophage fates through mitochondrial and metabolic remodeling. Red 625 nm irradiation induces glycolysis, mitochondrial fission, and M1 polarization, whereas near‐infrared 850 nm irradiation promotes fatty acid oxidation, mitochondrial fusion, and M2 polarization.
Qiusheng Shi   +12 more
wiley   +1 more source

Femtosecond‐Laser‐Induced Physical Unclonable Random Maze Structure for Storage‐Free Encryption

open access: yesAdvanced Science, EarlyView.
Femtosecond‐laser‐induced gold random maze structures serve as multimodal physical unclonable functions for storage‐free encryption. Their stochastic optical, electrical, and Raman responses are generated by plasmon‐assisted Marangoni formation and converted into AES‐compatible keys without permanent secret‐key storage, offering a portable route toward
Shiru Jiang   +6 more
wiley   +1 more source

UNIFICATION OF INFORMATION TECHNOLOGY TERMINOLOGY IN POLISH LAW – SELECTED ISSUES

open access: yesComparative Legilinguistics, 2012
In the present article the question of systematisation of information technology terminology in Polish Law is presented. The instrument, which is used for this purpose is the Amendment to Statutes in Order to Unify Information technology terminology Act
Filip RADONIEWICZ
doaj   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

open access: yesAdvanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami   +15 more
wiley   +1 more source

Legal constraints on technologies

open access: yes, 2020
The legal constraints of two important technologies for sustainable precision agriculture are presented: unmanned aircraft and artificial intelligence. Unmanned aircraft, or drones, are a rapidly developing technology. By 2035, it is estimated that in the EU, drones will create over 100,000 new jobs and produce more than 10 billion euros per year in ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy