Results 71 to 80 of about 260,158 (258)

Compliance Culture Shaping: The Way to Cultivate Compliance Awareness within the Enterprise [PDF]

SHS Web of Conferences
Shaping a compliance culture requires companies to establish an internal environment that promotes compliance with laws, regulations, and ethical norms.
Tian Zhen
doaj   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Legal analysis of the nature of the coordination rules in constitutions of the countries of Northern Europe

Контуры глобальных трансформаций: политика, экономика, право, 2015
The author for the first time used the coordination approach to the consideration of legal phenomena, through which we can examine the legal phenomenon from a new angle of view. The author conducts such research on the example of the constitutions of the
A. A. Maksurov
doaj  

Research on the Design Concept and Practice of Corporate Compliance Governance Systems [PDF]

SHS Web of Conferences
Considering the current global economic integration and the rapid development of the market economy, corporate compliance and governance involve compliance with legal regulations and many comprehensive issues, both internal and external.
Tian Zhen
doaj   +1 more source

Human Dental Pulp Stem Cell Secretome Restores Ischemic Stroke–Impaired Motor and Cognitive Functions by Reprogramming Redox and Inflammatory Signaling

Advanced Science, EarlyView.
Human dental pulp stem cell secretome emerges as a cell‐free therapeutic strategy for ischemic stroke by reprogramming redox and inflammatory signaling. hDPSC secretome‐derived antioxidant and immunomodulatory factors suppress the TLR4–NOX–ROS–NF‐κB axis, reduce microglial inflammatory responses and apoptosis, and promote neurogenesis, angiogenesis ...
Kyung‐Joo Seong, Sehoon Park, Sun‐Woong Bae, Daseul Kim, Jin Ho Lee, Won‐Seok Choi, Zee‐Yong Park, Ji‐Yeon Jung, Won‐Jae Kim   +8 more
wiley   +1 more source

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

Advanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng, Qiang Li, Haiyang Luo, Yapei Yuan, Na Zhang, Yongting Lu, Suying Duan, Jieshi Zhong, Hang Zhang, Chenyang Liu, Yaochong Zhang, Wenzhuo Zhao, Yaxuan Song, Tuo Wang, Si Yan, Yapeng Li, Han Liu, Yuan Gao, Zongping Xia, Yuming Xu   +19 more
wiley   +1 more source

New Frontiers in Clinical Legal Education: Harnessing Technology to Prepare Students for Practice and Facilitate Access to Justice

Australian Journal of Clinical Education, 2019
The increased use of technology in legal practice requires law schools to provide students with effective learning opportunities to prepare them for future practice.
Francina Cantatore
doaj   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

Countermeasures for legal issues to realize autonomous shipping

Nihon Kikai Gakkai ronbunshu, 2018
In recent years, engineering technology has become essential for our daily life. We cannot live without civil engineering or information technology even for one day.
Ayako UMEDA, Etsuro SHIMIZU, Kengo MINAMI, Toshiyuki MIYOSHI   +3 more
doaj   +1 more source

Reproductive technologies and the legal determination of fatherhood [PDF]

Feminist Legal Studies, 2005
In Re D is the most recent in a line of cases to have raised problems with the determination of legal fatherhood under s.28(3) of the Human Fertilisation and Embryology Act (1990). The judgment is interesting in particular as a demonstration of the growing currency of the idea that a child has a right to ‘genetic truth’ and for further evidencing a ...
openaire   +2 more sources