Results 61 to 70 of about 1,047,959 (349)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

The legend of the RMA: A trilogy [PDF]

open access: yes, 2003
In this presentation the author paints the conflict of people versus nature in light of the RMA, and go on to look at the repercussions of this through not only the plans that were prepared under this controversial legislation, but also their ...
Ericksen, Neil
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Preferences for post‐traumatic osteoarthritis prevention strategies in individuals with anterior cruciate ligament injury

open access: yesArthritis Care &Research, Accepted Article.
Objectives There is growing interest in evaluating new strategies to delay or prevent post‐traumatic osteoarthritis (PTOA) in individuals who have sustained anterior cruciate ligament (ACL) injury. This study sought to determine characteristics of potential treatments that are acceptable to patients with ACL injury.
Kevin Kennedy   +9 more
wiley   +1 more source

Interpretation of Historical Facts in Modern Italian Literature by the Example of Umberto Eco’s Novel “Baudolino”

open access: yesVestnik MGIMO-Universiteta, 2015
The article is devoted to interpretation of historical facts in Umberto Eco's novel " Baudolino ". The subject of interpretation in the novel is medieval history, in particular, the reign of the emperor Frederick Barbarossa.
Oxana Yu. Mushtanova
doaj   +2 more sources

Lilla Daam. Kogukonna usundiline muistend kui homogeenne tervik

open access: yesMäetagused, 2000
The article focuses on one particular ghost legend and its relations with the audience within a group of colleagues. Based on interviews, archival texts and the theoretical background of the contemporary legend research, the article points out the ...
Eda Kalmre
doaj  

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

The Legend of the Wehrmacht’s “Clean Hands”: The Attempt to Remove Nazism from the German Military

open access: yes, 2017
The legend of the Wehrmacht’s “clean hands” was created with the Himmerdoer Memorandum of 1950 and sought to disassociate the German military with its Nazi past.
McCracken, Kenneth R.
core  

Vimy: The Battle and the Legend (Book Review) by Tim Cook [PDF]

open access: yes, 2018
Review of Vimy: The Battle and the Legend by Tim ...
Pasierbek, Katrina J.
core   +1 more source

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