Results 41 to 50 of about 503,738 (282)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Myths and Legends of the Baldwin Effect [PDF]

open access: yes, 1996
This position paper argues that the Baldwin effect is widely misunderstood by the evolutionary computation community. The misunderstandings appear to fall into two general categories.
Turney, Peter
core   +3 more sources

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

University of Illinois Myths [PDF]

open access: yes, 2007
This project investigates the myths, legends, shocking facts, outrageous lies, and other stories told about the University of Illinois. The author seeks to answer the following questions: Are there ghost stories that maintain a firm grip on campus ...
Chontofalsky, Nichol
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Tolmini piirkonna kadunud järvedest jutustavate muistendite motiivid [PDF]

open access: yesMäetagused
The article discusses, from the content/motif aspect, 30 folk legends about the disappeared lakes in Tolmin region, Slovenia. The material covers different archival manuscripts and publications, mainly from Janez Dolenc’s student archive.
Barbara Ivančič Kutin
doaj   +1 more source

The Supernatural Beings of Belief Legends – Old Fears in a New Context

open access: yesStudia Mythologica Slavica, 2020
This paper examines the use of belief legends about witches, werewolves, and fairies at open-air festivals in Croatia today. At such events, traditions based on belief legends are invented with the idea of enriching local tourism not only as a source of ...
Luka Šešo
doaj   +1 more source

HISTORICAL MYTHOLOGY IN THE FIRST LITTLE RUSSIAN SHORT STORY OF N. GOGOL “EVENING ON THE EVE OF IVAN KUPALA” [PDF]

open access: yesПроблемы исторической поэтики, 2017
The article deals with Nikolai Gogol’s first novel “Evening on the Eve of Ivan Kupala” (1830), and studies the difference between its early and canonical editions, that argues for an attempt of an emerging author to create the “poetic history” of the ...
Vladimir D. Denisov
doaj   +1 more source

Selected Elements of Animated Nature Associated with the Birth of Jesus in the Bulgarian Oral Culture and Apocryphal Narratives [PDF]

open access: yes, 2014
Translated by Katarzyna GucioThe article attempts to extract textual and extratextual planes on which representatives of fauna made their mark in the folklore of the South Slavs, mainly Bulgarians; in their oral literature, rituals, and beliefs ...
Krzeszewska, Karolina
core  

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