Results 41 to 50 of about 10,125 (314)

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Determining Effective Color Combinations for Enhanced Legibility Presented on Print and Digital Formats

Applied Sciences
This study explores the impact of different color hue combinations and medium types (print and digital) on reading performance and comprehension. The purpose is to understand how these factors may influence text legibility and to offer practical insights
Petra Buljat, Dorotea Kovačević, Rahela Kulčar   +2 more
doaj   +1 more source

Personalized Legibility of an Indoor Environment for People with Motor Disabilities: A New Framework

ISPRS International Journal of Geo-Information, 2020
A mental map refers to the personalized representation of spatial knowledge in the human brain and is based on the perceptions, experiences, and interactions of people with their environment. For people with motor disabilities (PWMD) some perceptions and
Ali Afghantoloee, Mir Abolfazl Mostafavi, Geoffrey Edwards, Amin Gharebaghi   +3 more
doaj   +1 more source

Berberine–cinnamic acid co‐crystal effect in ameliorating hyperlipidemia might be regulated through the PI3K/AKT/mTOR/SREBP‐1 signaling pathway

FEBS Open Bio, EarlyView.
Berberine–cinnamic acid co‐crystal (BBR‐CA) inhibits the phosphorylation of the phosphatidylinositol 3‐kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) pathway, suppressing the transfer of pre‐sterol regulatory element‐binding proteins‐1 (SREBP‐1) from the endoplasmic reticulum to the nucleus. This results in a decrease in the expression level of
Wenheng Gao, Yunlong Li, Lihua Chen, Wenshuo Yang, Yong He, Ye Yang, Dengke Yin, Song Tan   +7 more
wiley   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Research on Safety and Static-Dynamic Legibility of Distressed Pavement

Discrete Dynamics in Nature and Society, 2015
In order to study the impacts of distressed pavement on driving safety, the drivers’ driving behavior and driving characteristics need to be analyzed. By analyzing the drivers’ characteristics, driving behavior’ and braking characteristics of vehicles ...
Chengyuan Mao, Yiming Bie, Yulong Pei, Weiwei Qi   +3 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

High incidence of medication documentation errors in a Swiss university hospital due to the handwritten prescription process

BMC Health Services Research, 2011
Background Medication errors have been reported to be a leading cause of death in hospitalized patients. In this study we focused on identifying and quantifying errors in the handwritten drug ordering and dispensing documentation processes which could ...
Röder Christoph, Staub Lukas P, Hartel Maximilian J, Eggli Stefan   +3 more
doaj   +1 more source

Handwriting legibility across different writing tasks in school-aged children

Hong Kong Journal of Occupational Therapy, 2022
Background: In school, children are required to perform a range of handwriting tasks. The writing needs to be legible to the child and other readers.
Yael Fogel, Sara Rosenblum, Anna L. Barnett   +2 more
doaj   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source