Results 51 to 60 of about 15,127 (304)
, 2016 Modern interfaces increasingly rely on screens filled with digital text to display information to users. Previous research has shown that even relatively subtle differences in the design of the on-screen typeface can influence to-device glance time in a ...
Zhao, Nan +4 more
core +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Robotics: Science and Systems IX, 2013 Legible motion --- motion that communicates its intent to a human observer --- is crucial for enabling seamless human-robot collaboration. In this paper, we propose a functional gradient optimization technique for autonomously generating legible motion.
Anca D. Dragan, Siddhartha S. Srinivasa
openaire +1 more source
, 1972 Three legibility factors were studied, using reading speed, comprehension and two other variables as criteria; these proved to be uncorrelated, raising questions concerning the meaning of “Legibility.”
Rodolfo N. Salcedo +3 more
core +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Legibility of Sans-Serif Typeface on Different Paper Grades Made from Invasive Alien Plant Species
Applied SciencesInvasive alien plant species (IAPS) may cause threats to native biodiversity in ecosystems. Researchers have been investigating all the possible ways that they can be used effectively for other purposes.
Klementina Možina +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Ambiguïtés, erreurs et conséquences : « Rendre l’œuvre lisible »
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2009 According to majors codes of ethic, the aim of restoration is to « facilitate the reading » or « the understanding » of the objects. The notion of legibility applied to paintings is questioned (and opposed to the notion of perception).
Michel Favre-Félix
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source