Results 71 to 80 of about 9,887 (314)
This study explores the impact of different color hue combinations and medium types (print and digital) on reading performance and comprehension. The purpose is to understand how these factors may influence text legibility and to offer practical insights
Petra Buljat +2 more
doaj +1 more source
The Effect of Font Characteristics on Large Format Display
Objective: To assess the legibility of a large set of existing large format display fonts. Background: The enormous selection of fonts allows for creative design; however, while there has been a lot of research on print and computer font legibility ...
Phillip M. Garvey +2 more
doaj +1 more source
Nerve Excitability in Asymptomatic Carriers and Amyotrophic Lateral Sclerosis Patients With C9orf72
ABSTRACT Objective We investigated the effects of C9orf72 mutation carriership on peripheral nerve excitability in asymptomatic individuals from families with a history of C9orf72 amyotrophic lateral sclerosis (ALS) and patients. Methods We included 47 asymptomatic individuals from families with a history of C9orf72 ALS, of whom 23 were carriers (C9 ...
Diederik J. L. Stikvoort García +3 more
wiley +1 more source
ABSTRACT Objective The optimal treatment for neurosarcoidosis myelitis is uncertain. We characterize incident neurosarcoidosis myelitis and assess treatment response by MRI and clinical scales. Methods Incident probable or definite neurosarcoidosis myelitis in adults was retrospectively identified from 13 academic medical centers.
Giovanna S. Manzano +39 more
wiley +1 more source
Background: The purpose of the study was to describe scores achieved by typical second-grade students on the Evaluation Tool of Children’s Handwriting – Manuscript and to compare scores with teacher perceptions.
Diane M. Long, James Conklin
doaj +1 more source
A model of character recognition and legibility. [PDF]
This article presents a model of character recognition and the experiments used to develop and test it. The model applies to foveal viewing of blurred or unblurred characters and to tactile sensing of raised characters using the fingerpad. The primary goal of the model is to account for variations in legibility across character sets; a secondary goal ...
openaire +3 more sources
Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge +4 more
wiley +1 more source
ABSTRACT Objective Natalizumab (NTZ) is a highly effective therapy for multiple sclerosis (MS); however, its use is limited by the risk of a rare potentially severe opportunistic brain infection, progressive multifocal leukoencephalopathy (PML). Alternative dosing strategies are evaluated to reduce PML risk while still maintaining efficacy, which ...
Regina Berkovich +10 more
wiley +1 more source
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann +6 more
wiley +1 more source
ABSTRACT Background Neurodegeneration with brain iron accumulation (NBIA) comprises a genetically and clinically heterogeneous group of rare neurological disorders characterized particularly by iron accumulation in the basal ganglia. To date, 15 genes have been associated with NBIA.
Seda Susgun +95 more
wiley +1 more source

