Investigation of Legionella Pneumophila bacteria in hospital water supply systems
Introduction: Legionella Pneumophila bacteria is known as one of the most important nosocomial infections and the most common cause of death in patients.
Maryam Moradnia +5 more
doaj
Legionella pneumophila strain associated with the first evidence of person-to-person transmission of Legionnaires’ disease: a unique mosaic genetic backbone [PDF]
A first strong evidence of person-to-person transmission of Legionnaires' Disease (LD) was recently reported. Here, we characterize the genetic backbone of this case-related Legionella pneumophila strain ("PtVFX/2014"), which also caused a large outbreak
Borges, Vítor +7 more
core +1 more source
NanoMLST is a workflow suggested as a viable alternative to high‐throughput ST determination for ESKAPE + E pathogens using ONT next‐generation sequencing. ABSTRACT Multi‐Locus Sequence Typing (MLST) is a key method for allocation of Sequence Types (STs) for bacterial isolates. Traditionally, this is performed by the Sanger sequencing method, which can
Isabel García‐Pérez +10 more
wiley +1 more source
Clinical and environmental distribution of legionella pneumophila in a university hospital in italy: efficacy of ultraviolet disinfection [PDF]
The molecular epidemiology of Legionella pneumophila in the 'V. Monaldi' University Hospital was studied. Seven cases of nosocomial Legionnaires' disease were diagnosed between 1999 and 2003.
Albanese Z +8 more
core +1 more source
Modulation of host cell pathways by Coxiella burnetii Dot/Icm effectors
Abstract Coxiella burnetii, the etiological agent of Q fever, is a significant intracellular bacterial pathogen. C. burnetii is a highly infectious pathogen that primarily targets pulmonary alveolar macrophages during natural infection. It can then disseminate to macrophages in other tissues and organs, leading to chronic infections. C.
Jingya Yuan +3 more
wiley +1 more source
Legionella colonization and 3D spatial location within a Pseudomonas biofilm
Biofilms are known to be critical for Legionella settlement in engineered water systems and are often associated with Legionnaire’s Disease events. One of the key features of biofilms is their heterogeneous three-dimensional structure which supports the ...
Ana Rosa Silva +3 more
doaj +1 more source
Intra-species and inter-kingdom signaling of Legionella pneumophila [PDF]
The ubiquitous Gram-negative bacterium Legionella pneumophila parasitizes environ mental amoebae and, upon inhalation, replicates in alveolar macrophages, thus causing a life-threatening pneumonia called "Legionnaires' disease." The opportunistic ...
Hilbi, Hubert, Hochstrasser, Ramon
core +2 more sources
Legionella pneumophila strain 130b possesses a unique combination of type IV secretion systems and novel Dot/Icm secretion system effector proteins [PDF]
Legionella pneumophila is a ubiquitous inhabitant of environmental water reservoirs. The bacteria infect a wide variety of protozoa and, after accidental inhalation, human alveolar macrophages, which can lead to severe pneumonia. The capability to thrive
Beatson, Scott A. +13 more
core +1 more source
Modulation of Rab GTPase function by a protein phosphocholine transferase. [PDF]
The intracellular pathogen Legionella pneumophila modulates the activity of host GTPases to direct the transport and assembly of the membrane-bound compartment in which it resides.
Arasaki, Kohei +5 more
core
Factors Influencing Legionella Contamination of Domestic Household Showers
Legionnaires’ disease is a potentially fatal pneumonia like infection caused by inhalation or aspiration of water particles contaminated with pathogenic Legionella spp.
Deanna Hayes-Phillips +3 more
doaj +1 more source

