Results 191 to 200 of about 30,447 (228)
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Intracellular Replication of Legionella pneumophila
Journal of Infectious Diseases, 1981Legionella pneumophila was inoculated onto tissue culture monolayers of MRC-5, HeLa, Hep 2, and McCoy cells. Fresh and conditioned medium without cells served as controls. Cultures were harvested at various times after inoculation, serial log10 dilutions were performed, and growth of L. pneumophila was quantitated either by direct immunofluorescence or
J A, Daisy +3 more
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Nosocomial infections with Legionella pneumophila
Journal of Hospital Infection, 1980The first recorded outbreak of Legionnaires’ disease occurred in a large psychiatric hospital in Washington DC in the summer of 1965. Here, 81 patients fell ill with acute pneumonia and 14 died, an attack rate of 1.4 per 100 patients. At postmortem, a number of the cases yielded Klebsiella pneumoniae on culture of purulent material from the lungs and K.
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Legionella pneumophila pathogenesis and immunity
Seminars in Pediatric Infectious Diseases, 2002Legionella pneumophila is a ubiquitous intracellular bacterium found widely in the environment and is the cause of sporadic outbursts of opportunistic infection, mainly in immunocompromised individuals, including young children as well as aged persons.
Herman, Friedman +2 more
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Oropharyngeal colonization with Legionella pneumophila
Journal of Clinical Microbiology, 1983A total of 186 volunteers, including 40 hospital patients, participated in a cross-sectional survey of oropharyngeal colonization with Legionella pneumophila. Colonization was defined as the appearance of any L. pneumophila organisms on culture or a positive direct fluorescent-antibody (FA) test or both in the absence of signs or symptoms of pneumonia.
J A, Bridge, P H, Edelstein
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Gene transfer in Legionella pneumophila
Microbes and Infection, 1999This review describes the mechanisms of gene transfer in Legionella pneumophila. To date, conjugation and transformation have been reported for this organism. Recent reports indicate that an endogenous system of plasmid transfer appears to be required for the intracellular survival and multiplication of L. pneumophila in host cells.
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Cell biology of Legionella pneumophila
Current Opinion in Microbiology, 1999Legionella pneumophila is the causative agent of a potentially fatal form of pneumonia named Legionnaires' disease. L. pneumophila survives and replicates inside macrophages by preventing phagosome-lysosome fusion. A large number of L. pneumophila genes, called dot or icm, have been identified that are required for intracellular growth. It has recently
J P, Vogel, R R, Isberg
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Iron Acquisition by Legionella pneumophila
BioMetals, 2006For nearly 20 years, it was believed that Legionella pneumophila does not produce siderophores. Yet, we have now determined that L. pneumophila secretes a siderophore (legiobactin) that is detectable by the CAS assay. We have optimized conditions for legiobactin expression, shown its biological activity, and found genes (lbtAB) involved in its ...
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Legionella Pneumophila Infection
Scottish Medical Journal, 1979R J, Fallon, N R, Grist, D, Reid
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