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Pleomorphism of Legionella Pneumophila

Ultrastructural Pathology, 1984
Legionella pneumophila (Lp), serogroups 1-6, was grown in vitro on a variety of media, in embryonated hens' eggs, and in guinea pigs. The morphology of the microbe was examined by light, immunofluorescent, and electron microscopy (transmission, scanning, negative staining).
S M, Katz   +4 more
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Autecology of Legionella pneumophila

Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale. A, Medizinische Mikrobiologie, Infektionskrankheiten und Parasitologie, 1983
Species of Legionella are readily isolated from freshwater aquatic habitats throughout the United States, which are diverse in their physical and chemical parameters. Temperature studies indicate that Legionella is not present in habitats with temperatures above 63 degrees C, and isolates have been obtained from frozen rivers.
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Legionella pneumophila pathogenesis and immunity

Seminars in Pediatric Infectious Diseases, 2002
Legionella pneumophila is a ubiquitous intracellular bacterium found widely in the environment and is the cause of sporadic outbursts of opportunistic infection, mainly in immunocompromised individuals, including young children as well as aged persons.
Herman, Friedman   +2 more
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Ferric reductases of Legionella pneumophila

Biometals, 1993
Ferric reductase enzymes requiring a reductant for maximal activity were purified from the cytoplasmic and periplasmic fractions of avirulent and virulent Legionella pneumophila. The cytoplasmic and periplasmic enzymes are inhibited by zinc sulfate, constitutive and active under aerobic or anaerobic conditions.
M T, Poch, W, Johnson
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Oropharyngeal colonization with Legionella pneumophila

Journal of Clinical Microbiology, 1983
A total of 186 volunteers, including 40 hospital patients, participated in a cross-sectional survey of oropharyngeal colonization with Legionella pneumophila. Colonization was defined as the appearance of any L. pneumophila organisms on culture or a positive direct fluorescent-antibody (FA) test or both in the absence of signs or symptoms of pneumonia.
J A, Bridge, P H, Edelstein
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Cell biology of Legionella pneumophila

Current Opinion in Microbiology, 1999
Legionella pneumophila is the causative agent of a potentially fatal form of pneumonia named Legionnaires' disease. L. pneumophila survives and replicates inside macrophages by preventing phagosome-lysosome fusion. A large number of L. pneumophila genes, called dot or icm, have been identified that are required for intracellular growth. It has recently
J P, Vogel, R R, Isberg
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Intracellular Replication of Legionella pneumophila

Journal of Infectious Diseases, 1981
Legionella pneumophila was inoculated onto tissue culture monolayers of MRC-5, HeLa, Hep 2, and McCoy cells. Fresh and conditioned medium without cells served as controls. Cultures were harvested at various times after inoculation, serial log10 dilutions were performed, and growth of L. pneumophila was quantitated either by direct immunofluorescence or
J A, Daisy   +3 more
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Metal requirements of Legionella pneumophila

Journal of Clinical Microbiology, 1981
Serial passage of six strains of Legionella pneumophila and one strain of Pseudomonas aeruginosa in a liquid chemically defined medium deficient in trace metals resulted in the death of five L. pneumophila strains and very limited growth in the remaining strain and the P. aeruginosa strain. Addition of either iron or magnesium restored growth to almost
M W, Reeves   +4 more
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Nosocomial infections with Legionella pneumophila

Journal of Hospital Infection, 1980
The first recorded outbreak of Legionnaires’ disease occurred in a large psychiatric hospital in Washington DC in the summer of 1965. Here, 81 patients fell ill with acute pneumonia and 14 died, an attack rate of 1.4 per 100 patients. At postmortem, a number of the cases yielded Klebsiella pneumoniae on culture of purulent material from the lungs and K.
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