Distribution of Legionella Species and Serogroups Isolated by Culture in Patients with Sporadic Community-Acquired Legionellosis: An International Collaborative Survey [PDF]
This international collaborative survey identified culture-confirmed legionellosis in 508 patients with sporadic community-acquired legionellosis. Legionella pneumophila constituted 91.5% of the isolates. Serogroup 1 was the predominant serogroup (84.2%),
Chereshsky, Annette +10 more
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Treadmill exercise improved METH‐induced learning and memory impairment in mice.Transcriptome analysis revealed that exercise modulated key pathways including PI3K‐Akt, mTOR, and Wnt signaling. NFKBIA, CXCL12, and Vav3 were identified as potential mediators of the beneficial effects.
Qiuyue Huang +6 more
wiley +1 more source
Molecular diversity and high virulence of Legionella pneumophila strains isolated from biofilms developed within a warm spring of a thermal spa. [PDF]
International audienceABSTRACT: BACKGROUND: Several cases of legionellosis have been diagnosed in the same French thermal spa in 1986, 1994 and 1997. L.
Atlan, Danièle +6 more
core +4 more sources
We proposed a novel computational method that can search for drug candidate compounds and generate new drug‐like structures considering cell‐specific gene expression patterns in diseased cells. The proposed method is expected to be useful for omics‐based drug discovery.
Chikashige Yamanaka +3 more
wiley +1 more source
Growth kinetics of environmental Legionella pneumophila isolated from industrial wastewater [PDF]
Wastewater treatment plants are environmental niches for Legionella pneumophila, the most commonly identified causative agent of severe pneumonia known as Legionnaire's disease. In the present study, Legionella pneumophila's concentrations were monitored
Caicedo, C. +3 more
core +1 more source
The Respiratory Tract Microbiome and Human Health
The respiratory tract microbiome (RTM) trains the immune system and protects against infections. Changes in the RTM are linked to various respiratory diseases. High‐throughput methodologies and computational biology can improve our understanding of the RTM, paving the way for new diagnostic tools, treatments and preventive strategies to improve ...
Patricia Fernández de Córdoba‐Ansón +4 more
wiley +1 more source
Legionnaires’ Disease Outbreaks and Cooling Towers, New York City, New York, USA
The incidence of Legionnaires’ disease in the United States has been increasing since 2000. Outbreaks and clusters are associated with decorative, recreational, domestic, and industrial water systems, with the largest outbreaks being caused by cooling ...
Robert Fitzhenry +15 more
doaj +1 more source
Communicable Disease Quarterly Report 2nd Qtr 2017 [PDF]
Communicable disease counts from 1930 to ...
core
DeepQA: A Unified Transcriptome‐Based Aging Clock Using Deep Neural Networks
DeepQA, a unified aging clock based on mixture of experts which is trained on both healthy and unhealthy subjects. ABSTRACT Understanding the complex biological process of aging is of great value, especially as it can help develop therapeutics to prolong healthy life.
Hongqian Qi +6 more
wiley +1 more source
Epidemiology of Legionnaires’ Disease, Hong Kong, China, 2005−2015
We reviewed findings of clinical, epidemiologic, and environmental investigations for 288 confirmed case-patients with Legionnaires’ disease reported in Hong Kong, China, during January 2005−December 2015.
Yiu-Hong Leung +4 more
doaj +1 more source

