Results 91 to 100 of about 3,754 (303)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2012 Based on recent studies of international military volunteering networks in the nineteenth Century, this article discusses the enrollment projects carried out by the Montevidean diplomacy in Europe during the last stage of the "Guerra Grande" (1848-1852 ...
Mario Etchechury Barrera
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Recruitment of Danubian Legions: X Gemina [PDF]
, 2014 Ovaj rad je zamišljen kao treći u nizu članaka posvećenih regrutaciji podunavskih legija u doba principata. Proces njihovog popunjavanja novim vojnicima tesno je povezan sa romanizacijom u provincijama u kojima su bile stacionirane. Malobrojni epigrafski
Ferjančić, Snežana
core
Receiver operating characteristic curves for the 5-point scoring method and the strain ratio method in differentiating malignant from benign legions for the lesions with elasticity score 3 and 4. [PDF]
, 2016 Receiver operating characteristic curves for the 5-point scoring method and the strain ratio method in differentiating malignant from benign legions for the lesions with elasticity score 3 and 4.
Shou-jun Liu (849384) +16 more
core +1 more source
The last legions: The “barbarization” of military identity in the Late Roman West
Tabula, 2016 Traditional scholarship has argued that during the fourth and fifth centuries the waning Roman Empire came to rely to a large extent on recruits of foreign, barbarian origin for its defence.
Vedran Bileta
doaj +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Peter S. WELLS, The Battle that stopped Rome. Emperor Augustus, Arminius, and the Slaughter of the Legions in the Teutoburg Forest. [PDF]
, 2006 Birley Anthony R. Peter S. WELLS, The Battle that stopped Rome. Emperor Augustus, Arminius, and the Slaughter of the Legions in the Teutoburg Forest. . In: L'antiquité classique, Tome 75, 2006. pp.
Birley, Anthony
core +2 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source