Results 171 to 180 of about 467,821 (313)

Human phase‐I metabolism of three synthetic cannabinoids bearing a cumyl moiety and a cyclobutyl methyl or norbornyl methyl tail: Cumyl‐CBMEGACLONE, Cumyl‐NBMEGACLONE, and Cumyl‐NBMINACA

Drug Testing and Analysis, EarlyView.
The human phase‐I metabolism of three SCRAs bearing a cumyl moiety and a CBM or NBM tail, based on LC‐qToF‐MS data of authentic urine specimens. Abstract Synthetic cannabinoid receptor agonists (SCRAs) continue to show high prevalence on the new psychoactive substances drug market.
Arianna Giorgetti, Pietro Brunetti, Belal Haschimi, Benedikt Pulver, Jennifer Paola Pascali, Jan Riedel, Volker Auwärter   +6 more
wiley   +1 more source

Advancing access to Medicare‐funded mental health treatment during the opioid epidemic: A counselor advocacy analysis

Journal of Counseling &Development, Volume 101, Issue 1, Page 15-28, January 2023., 2023
Abstract Although advocacy is a priority for counseling professionals, little is known about counseling advocates’ participation in the legislative advocacy process. Recent legislation to address the opioid crisis allowed counseling advocates to provide public comments to advance counselor inclusion in the Medicare program.
Jordan B. Westcott, Matthew C. Fullen, Justin Jordan   +2 more
wiley   +1 more source

Is the Food and Drug Administration Safe and Effective? [PDF]

In the United States, drug safety and efficacy are primarily regulated by the Food and Drug Administration (FDA) and the legal system, which gives manufacturers large incentives to produce safe drugs and provide proper warnings for side effects, since ...
Eric Sun, Tomas J. Philipson
core  

Waxy‐ or Putty‐Like Materials as a Novel Drug Preparation for Synthetic Cannabinoid Receptor Agonists: Detection in Prisons and In Vitro Cannabinoid Receptor Activity

Drug Testing and Analysis, EarlyView.
Waxy‐ or putty‐like materials has emerged as a novel drug preparation for synthetic cannabinoids and other drugs in UK prisons. An in vitro CB1 bioassay was used to evaluate the CB1 activating potential of MDMB‐INACA and extracts from eight seized samples. MDMB‐INACA had moderate efficacy but low potency at CB1.
Axelle Timmerman, Marie H. Deventer, Rachael Andrews, Robert Reid, Victoria Marland, Darren Edwards, Christopher R. Pudney, Niamh Nic Daéid, Christophe P. Stove, Caitlyn Norman   +9 more
wiley   +1 more source

“Even Though We Have Different Colors, We Are All Equal Here”: Immigrants building a sense of community and wellbeing through sport participation

Journal of Community Psychology, Volume 51, Issue 1, Page 201-218, January 2023., 2023
Abstract Although there are several studies reporting the beneficial role of sports in immigrant health, more research is needed to understand whether and how these activities can guide the psychological sense of community (SOC) and well‐being outcomes.
Chiara Corvino, Sara Martinez‐Damia, Mattia Belluzzi, Daniela Marzana, Chiara D'Angelo   +4 more
wiley   +1 more source

Identification and Investigation of the Intrinsic Receptor Activation Potential and Metabolization of the New Oxo‐Pyridyl Synthetic Cannabinoid Receptor Agonist CH‐FUBBMPDORA

Drug Testing and Analysis, EarlyView.
Another Chinese generic ban‐evading SCRA, CH‐FUBBMPDORA, has emerged. This study reports its first identification in Europe, its analytical characterization (NMR, Raman, FTIR, GC–MS, and HRMS), its cannabinoid activation potential in a βarr2 recruitment assay, and its metabolization profile.
Marie H. Deventer, Maria Carmela Emanuele, Brianna N. Stang, Katleen Van Uytfanghe, Jessica Masson, Xavier Bouvot, Catherine Lamoureux, Alessandro Proposito, Fabiano Reniero, Margaret V. Holland, Alex J. Krotulski, Luisa Mannina, Christophe P. Stove, Claude Guillou   +13 more
wiley   +1 more source

Barriers to access intimate partner violence services in female Romanian immigrants in Spain: A Delphi study

Journal of Community Psychology, Volume 51, Issue 1, Page 297-318, January 2023., 2023
Abstract Immigrant women may be at higher risk of intimate partner violence (IPV) and may seek specialized services less frequently than other populations. In Spain, Romanian origin foreigners comprise the second‐highest proportion among immigrant population.
Andrea Cuesta‐García, Violeta Fernández‐Lansac, María Crespo   +2 more
wiley   +1 more source

New challenges in assuring vaccine quality

Bulletin of the World Health Organization, 2000
In the past, quality control of vaccines depended on use of a variety of testing methods to ensure that the products were safe and potent. These methods were developed for vaccines whose safety and efficacy were based on several years worth of data ...
N. Dellepiane, E. Griffiths, J.B. Milstien   +2 more
doaj  

Screening and Quantification of the Synthetic Cannabinoid Receptor Agonist 5F‐MDMB‐PINACA From Seized Prison Paper Using Ultraperformance Liquid Chromatography–Mass Spectrometry Approaches

Drug Testing and Analysis, EarlyView.
Synthetic cannabinoid receptor agonists are being infused on paper and illicitly introduced into prisons through mail correspondence. An approach to quantify and map the synthetic cannabinoid 5F‐ADB on a seized paper sample from a UK prison was determined using ultraperformance liquid chromatography–quadrupole Dalton–mass spectrometry.
Giorgia Vaccaro, Jacqueline L. Stair, Stewart B. Kirton, Daniel Baker, Amira Guirguis   +4 more
wiley   +1 more source

Identification of Three Novel Tetrahydrocannabinol Analogs in the European Market

Drug Testing and Analysis, EarlyView.
The major isolated ingredient of “CB9” was identified as [2‐(E)‐propen‐1‐yl]‐Δ8‐tetrahydrocannabinol‐acetate of “tresconol” as [2‐propen‐2‐yl]‐Δ9‐tetrahydrocannabinol and of “CBx” as [2‐propen‐2‐yl]‐Δ8‐tetrahydrocannabinol. These compounds have no available spectroscopic or chromatographic data and have never been identified in Cannabis plants, and ...
Evangelos Dadiotis, Sotiris Mpakaoukas, Vangelis Mitsis, Eleni Melliou, Prokopios Magiatis   +4 more
wiley   +1 more source