Results 181 to 190 of about 467,821 (313)
Drug Testing and Analysis, EarlyView.A LC–MS/MS method has been validated for analysis of semi‐synthetic cannabinoids (SSC) and selected phytocannabinoids in seizures. Further SSC‐derivatives were implemented into the method for qualitative detection. The methodology was applied to a sample collective (n = 80) including cannabis flowers, resins, edibles and vape liquids.
Marica Hundertmark +4 more
wiley +1 more source
European Journal of Heart Failure, EarlyView.Lipidome changes in anthracycline‐induced cardiotoxicity (AIC). Aims Anthracyclines are key components of various chemotherapy regimens, but their clinical utility is limited by severe cardiotoxic side effects. Previous studies have suggested that anthracycline‐induced cardiotoxicity (AIC) may be driven by alterations in myocardial lipid metabolism ...
Vera M. Braun +6 more
wiley +1 more source
Review of Transcriptomic Biomarkers That Predict In Vitro Genotoxicity in Human Cell Lines
Environmental and Molecular Mutagenesis, EarlyView.ABSTRACT The current genotoxicity testing paradigm provides little mechanistic information, has poor specificity in predicting carcinogenicity in humans, and is not suited to assessing a large number of chemicals. Genomic technologies enable the characterization of genome‐wide transcriptional changes in response to chemical treatments that can inform ...
Heng‐Hong Li +7 more
wiley +1 more source
Proposed Food and Drug Legislation [PDF]
Journal of AOAC INTERNATIONAL, 1935 openaire +1 more source
Antiseizure medication choice in diffuse glioma: A single‐center population‐based experience
Epilepsia Open, EarlyView.Abstract Objective Several antiseizure medications (ASMs) can be considered as first‐line treatment for glioma‐associated epilepsy (GAE). We aimed to find out, if there are subgroups of glioma patients which may benefit from different first‐line ASMs. Methods All diffuse glioma (grade 2–4) patients, who were in contact with Helsinki University Hospital
Leena Ollila, Reina Roivainen
wiley +1 more source
Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines
Environmental Toxicology and Chemistry, EarlyView.Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz +4 more
wiley +1 more source
Through the lens of rural patients and pharmacies: A content analysis of state level pharmacy benefit manager regulations and policies. [PDF]
Explor Res Clin Soc PharmMelton TC +6 more
europepmc +1 more source
Environmental Toxicology and Chemistry, EarlyView.Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
State funding for cannabis research: an analysis of funding mechanisms and levels. [PDF]
J Cannabis ResBalla A, Boyle RG, Dempsey C.
europepmc +1 more source
Food Frontiers, EarlyView.This review examines how multiphase systems address the limitations of bio‐based and biodegradable polymers. It also discusses the application of various bio‐based polymers in developing these systems, highlighting their potential for sustainable food packaging solutions. ABSTRACT In recent decades, the thermoplastics market has experienced significant
Almas Mustafa +7 more
wiley +1 more source