Results 31 to 40 of about 111,424 (313)
Advanced Science, EarlyView.Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska +14 more
wiley +1 more source
Plants’ Impact on the Human Brain—Exploring the Neuroprotective and Neurotoxic Potential of Plants
PharmaceuticalsBackground: Plants have long been recognized for their potential to influence neurological health, with both neuroprotective and neurotoxic properties.
Georgiana Moise +8 more
doaj +1 more source
Advanced Science, EarlyView.Cigarette smoke accelerates the aging of immune cells in the lung. By combining human single‐cell sequencing, cell culture, and mouse models, the authors show that the protein GEM drives mitochondrial damage and senescence in alveolar macrophages by suppressing SIRT3.
Jin Wang +8 more
wiley +1 more source
Deterrence of drug driving: The impact of the ACT drug driving legislation and detection techniques
, 2014 The study sought to explore the initial impact of the ACT's implementation of roadside oral fluid drug screening program. The results suggest that a number of individuals reported intentions to drug drive in the future.
Watling, Christopher N. +2 more
core +1 more source
Coffea arabica: An Emerging Active Ingredient in Dermato-Cosmetic Applications
PharmaceuticalsBackground: Coffea arabica, commonly known as Arabica coffee, has garnered attention in recent years for its potential applications in dermato-cosmetic formulations. This review aims to critically evaluate the emerging role of Coffea arabica as an active
Grațiana Ruse +7 more
doaj +1 more source
Global Pediatric Drug Development
Current Therapeutic Research, 2019 : Background: The EU Paediatric Regulation was introduced in 2007. In the United States, specific paediatric legislation has existed for even longer. This overview describes the similarities and differences in the legislation and provides input on how ...
Mette Due Theilade Thomsen, PhD
doaj +1 more source
Políticas de drogas e o encarceramento de populações vulneráveis em Portugal e no Brasil
e-cadernos ces, 2022 This article seeks to understand aspects of the different forms of drug policy and its impact on vulnerable populations, focusing on incarceration in two different contexts, Portugal and Brazil.
Mayalu Matos Silva
doaj +1 more source
Advanced Science, EarlyView.Understanding how glomeruli, the kidney's filtration units, function in intact tissue remains challenging. Glomage enables rapid 3D imaging and quantitative analysis of entire glomeruli from zebrafish larvae and mice. This approach allows scalable cell quantification and detection of structural changes, advancing kidney disease research and ...
Maximilian Schindler +4 more
wiley +1 more source
LifeThe biological activity of Galium verum herba was exerted on various tumor cell lines with incredible results, but their potential effect on malignant melanoma has not been established yet.
Alexandra-Denisa Semenescu +9 more
doaj +1 more source
E.U. veterinary drug’s legislation [PDF]
Medicamentul Veterinar, 2008 The paper makes a short intoduction in veterinary drug’s legislation and presents de functioning mechanisms of European Medicines Agency(EMEA). There are presented EMEA’s structure, responsabilities, EU topicdefinitions and other specific aspects.
Cristina, T. Romeo
doaj