Results 31 to 40 of about 112,902 (166)

Global Pediatric Drug Development

Current Therapeutic Research, 2019
: Background: The EU Paediatric Regulation was introduced in 2007. In the United States, specific paediatric legislation has existed for even longer. This overview describes the similarities and differences in the legislation and provides input on how ...
Mette Due Theilade Thomsen, PhD
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Silibinin Triggers Mitochondrial Apoptosis and Declines Clonogenic Potential in Detroit 562 Human Pharyngeal Carcinoma Cells

Medicina
Background and Objectives: Oropharyngeal squamous cell carcinoma (OPSCC) is a common type of head and neck cancer with a progressive incidence in recent years.
Serban Talpos, Doina Chioran, George Cătălin Alexandru, Ștefania Dinu, Elena-Dorina Coricovac, Andreea Smeu, Diana Haj Ali, Camelia Szuhanek, Malina Popa   +8 more
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The determination of non-alcoholic substance use in drivers: Why? How? Where?

Psychiatry and Clinical Psychopharmacology, 2021
This article describes the background, legislations and new approaches in Turkey for control of drug use of drivers. In recent years, in parallel to the widespread use of illicit drugs, the number of drivers affected by drugs is also increasing.
Serap A. Akgür, A. Ender Altıntoprak, Zeki Yüncü, Hakan Çoşkunol   +3 more
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The effects of state rules on opioid prescribing in Indiana

BMC Health Services Research, 2018
Background Prescription opioids have been linked to over half of the 28,000 opioid overdose deaths in 2014. High rates of prescription opioid non-medical use have continued despite nearly all states implementing large-scale prescription drug monitoring ...
Morhaf Al Achkar, Shaun Grannis, Debra Revere, Palmer MacKie, Meredith Howard, Sumedha Gupta   +5 more
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Drug policy dilemma: ban or tolerance

Социологическая наука и социальная практика, 2016
Due to the significant change in drug situation in Russia and in the world, certain means of social control over distribution of drug consumption are analyzed.
Larisa N. Rybakova
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Influence of the legislation on the advertisement of psychoactive medications in Brazil

Brazilian Journal of Psychiatry, 2003
OBJECTIVE: The regulations on the advertisement of medications aim to encourage and promote an improved health care and the rational use of medications. The objective of this paper is to evaluate the influence of three regulations on the advertisement of
Mastroianni Patrícia de Carvalho, Galduróz Jose Carlos Fernandez, Carlini Elisaldo Araújo   +2 more
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Une « épidémie de drogue » en France dans les années 1960-1980 ?

Histoire, Médecine et Santé
In 1970, drug legislation was strengthened in France in a context where the press and politicians were denouncing a “drug epidemic.” The use of such a metaphor invites us to study both the number of drug addicts in France at that time and the social ...
Alexandre Marchant
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Puerarin-Loaded Proniosomal Gel: Formulation, Characterization, In Vitro Antimelanoma Cytotoxic Potential, and In Ovo Irritation Assessment

Gels
Puerarin is a naturally occurring isoflavone with reported anticancer activity, yet its topical translation is constrained by limited stability and suboptimal dermal delivery. A Puerarin-loaded proniosomal gel was developed as a potential dermal delivery
Sergio Liga, Andra Tămaș, Raluca Vodă, Gerlinde Rusu, Ioan Bîtcan, Vlad Socoliuc, Raluca Pop, Diana Haj Ali, Iasmina-Alexandra Predescu, Cristina Adriana Dehelean, Francisc Péter   +10 more
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Melissa officinalis L. (Lemon Balm): An Integrative Review of Phytochemistry and Evidence from Preclinical Research to Clinical Studies

Plants
Melissa officinalis L. (lemon balm) is a Lamiaceae species widely used in traditional and contemporary herbal practice, yet its reported bioactivities are strongly preparation-dependent, reflecting variability between polyphenol-rich extracts and ...
Ioan-Alexandru Cîmpeanu, Casiana Boru, Cristina Adriana Dehelean, Sergio Liga, Raluca Mioara Cosoroabă, Simona Ardelean, Roxana Popescu, Daliborca Vlad   +7 more
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Research on Approaches for Regulation of the “Off-label” use of Medicinal Products in the European Union

Acta Medica Bulgarica, 2017
Despite the increasingly strict legislation on medicinal products, the „off-label use“ or „use of medicinal product outside the approved summary of product characteristics (SmPC)“ is a weak point of today’s drug regulation and raises many questions about
Drenska M., Getov I.
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