The Medicare Prescription Drug, Improvement, & Modernization Act of 2003: Are We Playing the Lottery With Healthcare Reform? [PDF]
With millions of Americans unable to cope with the rising costs of prescription drugs, and many even forced to go without health insurance, the mounting pressure on Congress to enact major healthcare reform culminated in the Medicare Prescription Drug ...
Ganz, Melissa
core +1 more source
Subjective experiences of compulsory treatment from a qualitative study of early implementation of the Mental Health (Care and Treatment)(Scotland) Act 2003 [PDF]
Compulsory psychiatric treatment is highly contested, and little research has focused specifically on direct experiences. The Mental Health (Care & Treatment) (Scotland) Act, 2003 introduced new roles and provisions including community treatment orders,
Atkinson+39 more
core +1 more source
High in the City: A History of Drug Use in Mexico City, 1960-1980 [PDF]
This project analyzes drug use in Mexico City between 1960 and 1980, the decades when the Mexican state began criminalizing common drugs like marijuana, and prosecuting the consumers of legal drugs such as toxic inhalants.
Beckhart Coppinger, Sarah Elizabeth
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In multiple sclerosis, the disruption of the blood‐spinal cord barrier (BSCB) induced by CXCL13 facilitates the infiltration of inflammatory cells into the central nervous system, resulting in demyelination and neuronal injury. Mechanistically, the deleterious impact of CXCL13 on the BSCB is associated with a reduction in tight junction protein ...
Jingjing Han+10 more
wiley +1 more source
A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues
Abstract Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60 human myeloid leukemia cells by the resazurin assay.
Nikolett Gémes+10 more
wiley +1 more source
Alaska no hardship post: Cowper -- State licensing board investigates UAA School of Business instructor -- USUAJ election results -- S.E. campuses join forces -- Drug legislation proposed -- LETTERS -- The Juneau What? Newspaper? Valentine's Day; flowers,
core
This study highlights the critical role of IRF8 in the development of AAA. IRF8 activation promotes the differentiation of cDC1s, which in turn recruit and activate CD8+ T cells, contributing to aortic wall degradation. The study identifies the IRF8‐cDC1‐CD8+ T cell axis as a key pathway in AAA progression, offering new potential therapeutic targets to
Zhen Yuan+11 more
wiley +1 more source
Labelling of stock preparations and extemporaneous drugs: National and international legislation and practices [PDF]
The pharmaceutical industry has provided drug production of uniform quality, safety and efficacy, and the same is necessary for the preparation of stock preparations and extemporaneous drugs.
Vuleta Gordana+2 more
doaj +1 more source
NeuroCADR: Drug Repurposing to Reveal Novel Anti-Epileptic Drug Candidates Through an Integrated Computational Approach [PDF]
Drug repurposing is an emerging approach for drug discovery involving the reassignment of existing drugs for novel purposes. An alternative to the traditional de novo process of drug development, repurposed drugs are faster, cheaper, and less failure prone than drugs developed from traditional methods.
arxiv
Strong Support For Sununu, Drugs Remain Most Important Problem Facing NH 5/9/17 [PDF]
Governor Chris Sununu enjoys bipartisan approval of his job performance as well as increasing personal favorability among New Hampshire adults. A strong majority continue to believe overall the state is headed in the right direction, but for the first ...
Survey Center, UNH
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