Results 51 to 60 of about 876,168 (340)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini +13 more
wiley +1 more source
Measuring political legitimacy in two dimensions: internal and external measures
Frontiers in Political ScienceResearch on political legitimacy encompasses two distinct traditions, one institutionalist and another drawing on political culture accounts of legitimacy.
Philipp Harfst, Claudia Wiesner
doaj +1 more source
Thresholds are everywhere: A systems approach to public policy
BAR: Brazilian Administration Review, 2019 The analysis of public policies often fails to account for effects beyond mere cost-benefit analysis. Incorporating elements from the literature on system dynamics, complexity and legitimacy, the present paper develops a framework to understand long-term
Hamilton Coimbra Carvalho +2 more
doaj +1 more source
Misunderstood or lacking legitimacy? [PDF]
, 2007 In spite of the rising interest in marketing within professional service firms in the last twenty years, past research has identified a reluctant acceptance and application of marketing within these organisations.
Cohen, G, Sims, D
core
On Legitimacy: Designer as minor scientist [PDF]
, 2013 User experience research has recently been characterized in two camps, model-based and design-based, with contrasting approaches to measurement and evaluation.
Blythe, Mark, Ghassan, Aysar
core +3 more sources
Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
The legitimacy of regulation [PDF]
, 2003 I wish to address the topic of property rights and environmental regulation, chiefly the land use regulation that takes place when a rule is made in a plan under the Resource Management Act 1991, the RMA.
Barton, Barry
core +1 more source
Domain Specific Placebo Response in the Modified Friedreich's Ataxia Rating Scale
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The placebo response in clinical trials in ataxias complicates outcome interpretation and potentially obscures genuine treatment effects. We analyzed placebo group data from past trials in Friedreich Ataxia and observed notable responses in appendicular items, in contrast to minimal changes in axial function, as measured by respective ...
Christian Rummey +2 more
wiley +1 more source
Perspective Politice, 2019 There is a growing demand to change the institutions and constitutional design as response to the impact of the electorate or other recently emerging movements supported mostly from various street protest actions or citizens rallies.
Jana RESCHOVÁ
doaj
Adult‐Onset Subacute Sclerosing Panencephalitis Presenting With Subacute Cognitive Deficits
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT We describe the case of a 41‐year‐old man diagnosed with adult‐onset subacute sclerosing panencephalitis (SSPE). The patient presented with subacute progressive cognitive deficits and a neuropsychological profile indicating predominant frontoparietal dysfunction. MRI showed only mild parietal‐predominant cerebral atrophy.
Dennis Yeow +4 more
wiley +1 more source