Results 41 to 50 of about 870,071 (306)
Regional development and climate change adaptation: a study of the role of legitimacy [PDF]
, 2016 This paper presents results from a study of Czech Local Action Groups (LAGs), focusing on gaining knowledge about their internally perceived legitimacy and their potential role in local adaptation to climate change.
Danihelka, Pavel +4 more
core +2 more sources
Social Sciences, 2019 Dominant conceptions of solidarity economy, social enterprise, and innovation (SSEI) remain poorly positioned for understanding the diverse models emerging across the global South.
Sara Calvo Martínez +3 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Constitutional Legitimacy [PDF]
, 2003 The problem of constitutional legitimacy is to establish why anyone should obey the command of a constitutionally-valid law. A lawmaking system is legitimate if there is a prima facie duty to obey the laws it makes. Neither consent of the governed nor
Barnett, Randy E.
core +1 more source
On Legitimacy: Designer as minor scientist [PDF]
, 2013 User experience research has recently been characterized in two camps, model-based and design-based, with contrasting approaches to measurement and evaluation.
Blythe, Mark, Ghassan, Aysar
core +3 more sources
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Conservative Libertarianism and the Ethics of Borders
Tópicos, 2015 Many conservatives endorse a defence of closed borders grounded in basic liberal rights such as the basic right of association. Some conservatives also endorse libertarian principles of legitimacy.
Enrique Camacho Beltran
doaj +1 more source
A Comparative Analysis of the Islamic State and the Muslim State through Historical Developments [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2020 Discussions about the relationship between religion and state or religion and politics in the contemporary era have been discussed more than in any other period, especially in relation to the religion of Islam.
Masoud Akhavan Kazemi
doaj +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Frontiers in Political ScienceThe paper outlines key points of a novel research approach to empirically investigate the question of legitimacy in modern societies. This new research approach utilizes a functionalist perspective to expand the concept of legitimacy.
Zsófia S. Ignácz
doaj +1 more source