Results 31 to 40 of about 59,164,126 (252)

Caregiver Perspectives on the Burden of Disease and Treatment in Uncontrolled Gout

open access: yesArthritis Care &Research, EarlyView.
Objective Uncontrolled gout (UG) refers to persistently elevated serum urate (SU) levels >6 mg/dL and ongoing gout symptoms despite use of urate‐lowering therapy (ULT). The objective of this study was to evaluate the burden associated with informal caregiving for individuals with UG.
Angelo Gaffo   +6 more
wiley   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Lei de Brandford: uma reformulação conceitual

open access: yesCiência da Informação, 1983
A lei de Bradford, mesmo com reformulações de outros autores, não corresponde, ainda, à realidade do comportamento da literatura científica. Pretende-se alterar a parte conceituai, independentemente de sua representação matemática e gráfica, para ...
Lena Vânia Ribeiro Pinheiro
doaj  

Produção científica sobre gestão do conhecimento e gestão da informação no âmbito da Ciência da Informação: uma aplicação da lei de Bradford

open access: yesAnales de Documentación, 2012
Objetivou-se analisar a produção científica sobre gestão da informação e gestão do conhecimento nos periódicos mais relevantes da área de Ciência da Informação, observando assim a relevância e impacto destes para esta área de conhecimento. A pesquisa, de
Mariana Lousada   +5 more
doaj   +1 more source

First M87 Event Horizon Telescope Results. VII. Polarization of the Ring

open access: yesThe Astrophysical Journal Letters, 2021
In 2017 April, the Event Horizon Telescope (EHT) observed the near-horizon region around the supermassive black hole at the core of the M87 galaxy. These 1.3 mm wavelength observations revealed a compact asymmetric ring-like source morphology.
The Event Horizon Telescope Collaboration   +240 more
doaj   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

open access: yesAdvanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park   +5 more
wiley   +1 more source

First M87 Event Horizon Telescope Results. VIII. Magnetic Field Structure near The Event Horizon

open access: yesThe Astrophysical Journal Letters, 2021
Event Horizon Telescope (EHT) observations at 230 GHz have now imaged polarized emission around the supermassive black hole in M87 on event-horizon scales.
The Event Horizon Telescope Collaboration   +241 more
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

open access: yesAdvanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes   +14 more
wiley   +1 more source

Aplicação da lei de Bradford à literatura técnica sobre ferrovia: análise de periódicos e avaliação da base de dados da Rede Ferroviária Federal S.A.

open access: yesCiência da Informação, 1991
A lei de Bradford foi aplicada à fonte secundária, produto da base de dados da Rede Ferroviária Federal S.A. Os periódicos integrantes da distribuição foram analisados segundo país de origem e idioma, destacando-se os elementos que podem interferir na ...
Eliana Coutinho
doaj  

Polarimetric Properties of Event Horizon Telescope Targets from ALMA

open access: yesThe Astrophysical Journal Letters, 2021
We present the results from a full polarization study carried out with the Atacama Large Millimeter/submillimeter Array (ALMA) during the first Very Long Baseline Interferometry (VLBI) campaign, which was conducted in 2017 April in the λ 3 mm and λ 1.3 ...
Ciriaco Goddi   +249 more
doaj   +1 more source

Home - About - Disclaimer - Privacy